共 21 条
Stimulated Hofbauer cells in the placental villi from patients with second-trimester abortions
被引:7
作者:
Matsubara, S
[1
]
Minakami, H
Yamada, T
Koike, T
Izumi, A
Takizawa, T
Saito, T
Sato, K
机构:
[1] Jichi Med Sch, Dept Obstet & Gynecol, Minami Kawachi, Tochigi 3290498, Japan
[2] Jichi Med Sch, Dept Anat, Minami Kawachi, Tochigi 3290498, Japan
关键词:
Hofbauer cells;
placenta;
abortion;
acid phosphatase;
D O I:
10.1267/ahc.31.447
中图分类号:
Q2 [细胞生物学];
学科分类号:
071009 ;
090102 ;
摘要:
The purpose of this study was to characterize the ultrastructural and enzyme-histochemical features of Hofbauer cells in the placental villi of second-trimester abortions. Hofbauer cells in the abortive placenta had more numerous cytoplasmic processes and more prominent phagosomes as compared to gestational age-matched normal control placenta. Acid phosphatase activity was demonstrated in both the lysosomes and on phagosomal membranes of these cells. Our results indicate that Hofbauer cells in second-trimester abortions are activated or stimulated in situ. These activated Hofbauer cells might play important roles in the pathophysiology of preterm parturition.
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页码:447 / 452
页数:6
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