Stimulated Hofbauer cells in the placental villi from patients with second-trimester abortions

被引:7
作者
Matsubara, S [1 ]
Minakami, H
Yamada, T
Koike, T
Izumi, A
Takizawa, T
Saito, T
Sato, K
机构
[1] Jichi Med Sch, Dept Obstet & Gynecol, Minami Kawachi, Tochigi 3290498, Japan
[2] Jichi Med Sch, Dept Anat, Minami Kawachi, Tochigi 3290498, Japan
关键词
Hofbauer cells; placenta; abortion; acid phosphatase;
D O I
10.1267/ahc.31.447
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The purpose of this study was to characterize the ultrastructural and enzyme-histochemical features of Hofbauer cells in the placental villi of second-trimester abortions. Hofbauer cells in the abortive placenta had more numerous cytoplasmic processes and more prominent phagosomes as compared to gestational age-matched normal control placenta. Acid phosphatase activity was demonstrated in both the lysosomes and on phagosomal membranes of these cells. Our results indicate that Hofbauer cells in second-trimester abortions are activated or stimulated in situ. These activated Hofbauer cells might play important roles in the pathophysiology of preterm parturition.
引用
收藏
页码:447 / 452
页数:6
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