Atrial Fibrillation and Gastro-Oesophageal Reflux Disease - Controversies and Challenges

被引：9

作者：

Floria, Mariana ^{[1
]}

Barboi, Oana ^{[2
,3
]}

Rezus, Ciprian ^{[1
]}

Ambarus, Valentin ^{[1
]}

Cijevschi-Prelipcean, Cristina ^{[2
,3
]}

Balan, Gheor-Ghe ^{[2
,3
]}

Drug, Vasile Liviu ^{[2
,3
]}

机构：

[1] III Med Clin, Iasi, Romania

[2] Sf Spiridon Univ Hosp Iasi, Gastroenterol & Hepathol Inst, Iasi 700111, Romania

[3] Grigore T Popa Univ Med & Pharm, Iasi, Romania

来源：

CURRENT PHARMACEUTICAL DESIGN | 2015年 / 21卷 / 26期

关键词：

Atrial fibrillation; gastro-oesophageal reflux disease; inflammation; vagal stimulation; RADIOFREQUENCY CATHETER ABLATION; C-REACTIVE PROTEIN; RISK-FACTOR; ELECTRICAL CARDIOVERSION; NEUROCARDIAC FUNCTION; AUTONOMIC MODULATION; METABOLIC SYNDROME; RECURRENCE; HEART; ESOPHAGITIS;

D O I：

10.2174/1381612821666150319100003

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Atrial fibrillation and gastro-oesophageal reflux are common manifestations in daily practice. The atria and the oesophagus are closely located and have similar nerve innervations. Over the last years, it has been observed that atrial fibrillation development and reflux disease could be related. Atrial fibrillation occurrence could be due to vagal nerve overstimulation. This, in association with vagal nerve-mediated parasympathetic stimulation, has also been observed in patients with gastro-oesophageal reflux. These mechanisms, in addition to inflammation, seem to be implicated in the pathophysiology of both diseases. Despite these associations supported by clinical and experimental studies, this relationship is still considered controversial. This review summarizes critical data regarding the association of gastro-oesophageal reflux and atrial fibrillation as well as their clinical implications.

引用

页码：3829 / 3834

页数：6

共 73 条

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