Recurrent Glomerular Disease after Kidney Transplantation: Diagnostic and Management Dilemmas

被引：42

作者：

Uffing, Audrey ^{[1
,2
]}

Hullekes, Frank ^{[1
]}

Riella, Leonardo, V ^{[1
,3
]}

Hogan, Jonathan J. ^{[4
]}

机构：

[1] Harvard Med Sch, Massachusetts Gen Hosp, Renal Div, Sch,55 Fruit St, Boston, MA 02114 USA

[2] Univ Groningen, Univ Med Ctr Groningen, Dept Nephrol, Groningen, Netherlands

[3] Massachusetts Gen Hosp, Ctr Transplantat Sci, Dept Surg, Boston, MA 02114 USA

[4] Univ Penn, Perelman Sch Med, Div Renal Electrolyte & Hypertens, Philadelphia, PA 19104 USA

来源：

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | 2021年 / 16卷 / 11期

基金：

美国国家卫生研究院;

关键词：

glomerulonephritis; kidney transplantation; glomerular disease; allograft failure; recurrent glomerular disease; kidney transplantation series; FOCAL SEGMENTAL GLOMERULOSCLEROSIS; PHOSPHOLIPASE-A2 RECEPTOR AUTOANTIBODIES; IDIOPATHIC MEMBRANOUS NEPHROPATHY; CONGENITAL NEPHROTIC SYNDROME; RENAL-TRANSPLANTATION; IGA NEPHROPATHY; PLASMA-EXCHANGE; PRIMARY GLOMERULONEPHRITIS; ALLOGRAFT SURVIVAL; NATIVE NEPHRECTOMY;

D O I：

10.2215/CJN.00280121

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Recurrent glomerular disease after kidney transplant remains an important cause of allograft failure. Many of the different entities post-transplant still suffer from incomplete knowledge on pathophysiology, and therefore lack targeted and effective therapies. In this review, we focus on specific clinical dilemmas encountered by physicians in managing recurrent glomerular disease by highlighting new insights into the understanding and treatment of post-transplant focal segmental glomerulosclerosis, membranous nephropathy, atypical hemolytic uremic syndrome, C3 glomerulopathy, amyloid light-chain (AL) amyloidosis, and IgA nephropathy.

引用

页码：1730 / 1742

页数：13

共 97 条

[1] Podocyte Effacement Closely Links to suPAR Levels at Time of Posttransplantation Focal Segmental Glomerulosclerosis Occurrence and Improves With Therapy [J].

Alachkar, Nada ;

Wei, Changli ;

Arend, Lois J. ;

Jackson, Annette M. ;

Racusen, Lorraine C. ;

Fornoni, Alessia ;

Burke, George ;

Rabb, Hamid ;

Kakkad, Kavita ;

Reiser, Jochen ;

Estrella, Michelle M. .

TRANSPLANTATION, 2013, 96 (07) :649-656

[2] Rituximab and Therapeutic Plasma Exchange in Recurrent Focal Segmental Glomerulosclerosis Postkidney Transplantation [J].

Alasfar, Sami ;

Matar, Dany ;

Montgomery, Robert A. ;

Desai, Niraj ;

Lonze, Bonnie ;

Vujjini, Vikas ;

Estrella, Michelle M. ;

Dieck, John Manllo ;

Khneizer, Gebran ;

Sever, Sanja ;

Reiser, Jochen ;

Alachkar, Nada .

TRANSPLANTATION, 2018, 102 (03) :e115-e120

[3] ACTH Gel in Resistant Focal Segmental Glomerulosclerosis After Kidney Transplantation [J].

Alhamad, Tarek ;

Dieck, John Manllo ;

Younus, Usman ;

Matar, Dany ;

Alasfar, Sami ;

Vujjini, Vikas ;

Wall, Devin ;

Kanawati, Bilal ;

Reiser, Jochen ;

Brennan, Daniel C. ;

Alachkar, Nada .

TRANSPLANTATION, 2019, 103 (01) :202-209

[4] Treatment by immunoadsorption for recurrent focal segmental glomerulosclerosis after paediatric kidney transplantation: a multicentre French cohort [J].

Allard, Lise ;

Kwon, Theresa ;

Krid, Saoussen ;

Bacchetta, Justine ;

Garnier, Arnaud ;

Novo, Robert ;

Deschenes, Georges ;

Salomon, Remi ;

Roussey, Gwenaelle ;

Allain-Launay, Emma .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2018, 33 (06) :954-963

[5] Recurrent glomerulonephritis after kidney transplantation: risk factors and allograft outcomes [J].

Allen, Penelope J. ;

Chadban, Steve J. ;

Craig, Jonathan C. ;

Lim, Wai H. ;

Allen, Richard D. M. ;

Clayton, Philip A. ;

Teixeira-Pinto, Armando ;

Wong, Germaine .

KIDNEY INTERNATIONAL, 2017, 92 (02) :461-469

[6] Long-term outcome of kidney transplantation in AL amyloidosis [J].

Angel-Korman, Avital ;

Stern, Lauren ;

Sarosiek, Shayna ;

Sloan, J. Mark ;

Doros, Gheorghe ;

Sanchorawala, Vaishali ;

Havasi, Andrea .

KIDNEY INTERNATIONAL, 2019, 95 (02) :405-411

[7] Bortezomib as a Novel Approach to Early Recurrent Membranous Glomerulonephritis After Kidney Transplant Refractory to Combined Conventional Rituximab Therapy [J].

Barbari, Antoine ;

Chehadi, Rima ;

Assouf, Hala Kfoury ;

Kamel, Gaby ;

Jaafar, Mahassen ;

Abdallah, Ayman ;

Rizk, Sylvana ;

Masri, Marwan .

EXPERIMENTAL AND CLINICAL TRANSPLANTATION, 2017, 15 (03) :350-354

[8] A propensity score matched analysis shows no adverse effect of early steroid withdrawal in non-diabetic kidney transplant recipients with and without glomerulonephritis [J].

Barbour, Sean ;

Djurdjev, Ognjenka ;

Gill, John S. ;

Dong, Jianghu James ;

Gill, Jagbir .

KIDNEY INTERNATIONAL, 2019, 96 (02) :460-469

[9] M-Type Phospholipase A(sub 2) Receptor as Target Antigen in Idiopathic Membranous Nephropathy. [J].

Beck, Laurence H., Jr. ;

Bonegio, Ramon G. B. ;

Lambeau, Gerard ;

Beck, David M. ;

Powell, David W. ;

Cummins, Timothy D. ;

Klein, Jon B. ;

Salant, David J. .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (01) :11-21

[10] Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice [J].

Beckerman, Pazit ;

Bi-Karchin, Jing ;

Park, Ae Seo Deok ;

Qiu, Chengxiang ;

Dummer, Patrick D. ;

Soomro, Irfana ;

Boustany-Kari, Carine M. ;

Pullen, Steven S. ;

Miner, Jeffrey H. ;

Hu, Chien-An A. ;

Rohacs, Tibor ;

Inoue, Kazunori ;

Ishibe, Shuta ;

Saleem, Moin A. ;

Palmer, Matthew B. ;

Cuervo, Ana Maria ;

Kopp, Jeffrey B. ;

Susztak, Katalin .

NATURE MEDICINE, 2017, 23 (04) :429-+

← 1 2 3 4 5 6 7 8 9 10 →