Antioxidant Activity and Free Radical Scavenging Properties of Captopril

被引：0
|
作者：
Asori, Mohsen [1 ]
Hedayatizadeh-Omran, Akbar [1 ]
机构：
[1] Mazandaran Univ Med Sci, Sari, Iran
来源：
ASIAN JOURNAL OF CHEMISTRY | 2011年 / 23卷 / 08期
关键词：
Captopril; Oxidative stress; Free radical scavenging; Reducing power; CONVERTING ENZYME-INHIBITOR; BONE-MARROW-CELLS; OXIDATIVE STRESS; PLANT-EXTRACTS; CANCER-THERAPY; IN-VITRO; GENOTOXICITY; INFLAMMATION; APOPTOSIS;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Several diseases are associated with oxidative stress caused by free radicals and reactive oxygen species. In this study, antioxidant activity of captopril was studied using in vitro assays systems. Free radical scavenging and reducing power were determined with diphenyl picryl hydrazyl free radical (DPPH method) and potassium ferricyanide method, respectively. The results of this study showed that captopril possessed a significant free radical scavenging and reducing power properties and there were a clear correlation exists between antioxidant activity and concentration of captopril. Percentage of free radical scavenging of captopril was more than 92 % at concentration 0.08 mM.
引用
收藏
页码：3713 / 3715
页数：3
相关论文
共 50 条
  • [21] An Organoselenium Drug with Antioxidant Activity and Free Radical Scavenging Capacity In Vitro
    Mohammad Ibrahim
    Waseem Hassan
    Anna Maria Deobald
    Antonio Luis Braga
    Joao B. T. Rocha
    Biological Trace Element Research, 2012, 149 : 399 - 404
  • [22] Antioxidant and free radical scavenging activity of an aqueous extract of Coleus aromaticus
    Kumaran, A
    Karunakaran, RJ
    FOOD CHEMISTRY, 2006, 97 (01) : 109 - 114
  • [23] Free radical scavenging (antioxidant activity) of natural dissolved organic matter
    Romera-Castillo, Cristina
    Jaffe, Rudolf
    MARINE CHEMISTRY, 2015, 177 : 668 - 676
  • [24] Irradiation effects on free radical scavenging and antioxidant activity of phytic acid
    Ahn, HJ
    Kim, JH
    Yook, HS
    Byun, MW
    JOURNAL OF FOOD SCIENCE, 2003, 68 (07) : 2221 - 2224
  • [25] Antioxidant and Free Radical Scavenging Activity of Phenolics from Bidens humilis
    Saltos, Mariela Beatriz Vera
    Puente, Blanca Fabiola Naranjo
    Milella, Luigi
    De Tommasi, Nunziatina
    Dal Piaz, Fabrizio
    Braca, Alessandra
    PLANTA MEDICA, 2015, 81 (12-13) : 1056 - 1064
  • [26] In Vitro Antioxidant and Free Radical Scavenging Activity of Nardostachys jatamansi DC
    Sharma, Surendra Kumar
    Singh, Ajay Pal
    JOURNAL OF ACUPUNCTURE AND MERIDIAN STUDIES, 2012, 5 (03) : 112 - 118
  • [27] Chemical studies on antioxidant mechanisms and free radical scavenging properties of lignans
    Eklund, PC
    Långvik, OK
    Wärnå, JP
    Salmi, TO
    Willför, SM
    Sjöholm, RE
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2005, 3 (18) : 3336 - 3347
  • [28] Antioxidant and radical scavenging properties of curcumin
    Ak, Tuba
    Gulcin, Ilhami
    CHEMICO-BIOLOGICAL INTERACTIONS, 2008, 174 (01) : 27 - 37
  • [29] Antioxidant and Free Radical Scavenging Activities of Curcumin
    Asouri, Mohsen
    Ataee, Ramin
    Ahmadi, Ali Asghar
    Amini, Abdolhossein
    Moshaei, Masoumeh Rezaei
    ASIAN JOURNAL OF CHEMISTRY, 2013, 25 (13) : 7593 - 7595
  • [30] Proanthocyanidin microcapsules:: preparation, properties and free radical scavenging activity
    Andry, MC
    Vezin, H
    Dumistracel, I
    Bernier, JL
    Lévy, MC
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1998, 171 (02) : 217 - 226
12345