Antioxidant Activity and Free Radical Scavenging Properties of Captopril

被引：0
|
作者：
Asori, Mohsen [1 ]
Hedayatizadeh-Omran, Akbar [1 ]
机构：
[1] Mazandaran Univ Med Sci, Sari, Iran
来源：
ASIAN JOURNAL OF CHEMISTRY | 2011年 / 23卷 / 08期
关键词：
Captopril; Oxidative stress; Free radical scavenging; Reducing power; CONVERTING ENZYME-INHIBITOR; BONE-MARROW-CELLS; OXIDATIVE STRESS; PLANT-EXTRACTS; CANCER-THERAPY; IN-VITRO; GENOTOXICITY; INFLAMMATION; APOPTOSIS;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Several diseases are associated with oxidative stress caused by free radicals and reactive oxygen species. In this study, antioxidant activity of captopril was studied using in vitro assays systems. Free radical scavenging and reducing power were determined with diphenyl picryl hydrazyl free radical (DPPH method) and potassium ferricyanide method, respectively. The results of this study showed that captopril possessed a significant free radical scavenging and reducing power properties and there were a clear correlation exists between antioxidant activity and concentration of captopril. Percentage of free radical scavenging of captopril was more than 92 % at concentration 0.08 mM.
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收藏
页码：3713 / 3715
页数：3
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