TREATMENT OF SEVERE CHROMOBLASTOMYCOSIS WITH ITRACONAZOLE AND 5-FLUCYTOSINE ASSOCIATION

被引：19

作者：

Antonello, Vicente Sperb ^{[1
]}

Appel da Silva, Marcelo Campos ^{[2
]}

Cambruzzi, Eduardo ^{[3
]}

Kliemann, Dimas Alexandre ^{[1
]}

Santos, Breno Riegel ^{[1
]}

Queiroz-Telles, Flavio ^{[4
]}

机构：

[1] Hosp Nossa Senhora Conceicao, Dept Infect Dis, Porto Alegre, RS, Brazil

[2] Hosp Nossa Senhora Conceicao, Dept Internal Med, Porto Alegre, RS, Brazil

[3] Hosp Nossa Senhora Conceicao, Dept Pathol, Porto Alegre, RS, Brazil

[4] Univ Fed Parana, Hosp Clin, Dept Community Hlth & Infect Dis, BR-80060000 Curitiba, PR, Brazil

来源：

REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO | 2010年 / 52卷 / 06期

关键词：

Chromoblastomycosis; Itraconazole; 5-Flucytosine; Subcutaneous mycoses; AMPHOTERICIN-B; 5-FLUOROCYTOSINE; MYCOSES;

D O I：

10.1590/S0036-46652010000600008

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Chromoblastomycosis is a chronic human melanized fungi infection of the subcutaneous tissue caused by traumatic inoculation of a specific group of dematiaceous fungi through the skin, often found in barefooted agricultural workers, in tropical and subtropical climate countries. We report the case of a male patient presenting a slow-growing pruriginous lesion on the limbs for 20 years, mistreated over that time, which was diagnosed and successfully treated as chromoblastomycosis. Besides the prevalence of this disease, treatment is still a clinical challenge.

引用

页码：329 / 331

页数：3

共 23 条

[1] Chromoblastomycosis: clinical presentation and management [J].

Ameen, M. .

CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2009, 34 (08) :849-854

[2]

Bayles MAH, 1989, BALLIERES CLIN TROPI, P45

[3]

Bennet JohnE., 2005, Goodman and Gilman Pharmacological basis of therapeutics, V11th, P1225

[4] FLUCYTOSINE [J].

BENNETT, JE .

ANNALS OF INTERNAL MEDICINE, 1977, 86 (03) :319-322

[5]

BLOCK ER, 1973, P SOC EXP BIOL MED, V142, P476, DOI 10.3181/00379727-142-37049

[6]

Bolzinger T., 1991, Novo Dermatol, V10, P462

[7] Treating chromoblastomycosis with systemic antifungals [J].

Bonifaz, A ;

Paredes-Solís, V ;

Saúl, A .

EXPERT OPINION ON PHARMACOTHERAPY, 2004, 5 (02) :247-254

[8]

Bopp C, 1976, Med Cutan Ibero Lat Am, V4, P285

[9]

BORELLI D, 1987, REV INFECT DIS, V9, pS57

[10] Treatment of chromomycosis by cryosurgery with liquid nitrogen: 15 years' experience [J].

Castro, LGM ;

Pimentel, ERA ;

Lacaz, CS .

INTERNATIONAL JOURNAL OF DERMATOLOGY, 2003, 42 (05) :408-412

← 1 2 3 →