NON-TUBERCULOUS MYCOBACTERIAL PULMONARY DISEASE: AN ITALIAN NATIONAL SURVEY

被引:0
作者
Del Prato, Bruno [1 ]
Altieri, Alfonso Maria [2 ]
Carlucci, Biagio [3 ]
Mori, Pier Anselmo [4 ]
Parrella, Roberto [5 ]
Stainer, Anna [6 ]
De Giacomi, Federica [6 ]
Pesci, Alberto [6 ]
Faverio, Paola [6 ]
机构
[1] UOSC Pneumol Interventist AORNA Cardarelli, Naples, Italy
[2] AOS Camillo Forlanini, UOC Broncopneumol & Tisiol, Rome, Italy
[3] Osped Madonna delle Grazie, UOC Pneumol UTIR, Matera, Italy
[4] Univ Parma, Azienda Osped, UOC Pneumol & Endoscopia Torac, Parma, Italy
[5] AORN Colli Cotugno Hosp, UOC Malattie Infett & Indirizzo Resp, Naples, Italy
[6] Univ Milano Bicocca, San Gerardo Hosp, Resp Unit, ASST Monza,Dipartimento Cardiotoracovasc, Via Pergolesi 33, I-20900 Monza, Italy
关键词
non-tuberculous mycobacterial pulmonary disease; epidemiology; survey; AVIUM COMPLEX;
D O I
暂无
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
The incidence of non-tuberculous mycobacteria (NTM) infection is increasing in Europe. However, a picture of Italian epidemiology and clinical practice is missing. We performed a national Italian survey involving 42 respiratory medicine departments. The NTM species more frequently isolated were Mycobacterium avium complex, followed by M. xenopi and M. kansasii. Patients with NTM were more frequently female (57%), and over 60 years of age, with bronchiectasis and COPD as main comorbidities. Bronchoscopic samples were widely used in the diagnostic phase. Of all patients with NTM, 73% met the criteria for NTM pulmonary disease. Despite strong adherence to the guidelines, physicians found significant difficulties related to pharmacological adverse events, patients' compliance and poor outcomes.
引用
收藏
页码:21 / 25
页数:5
相关论文
共 7 条
[1]   Characterizing Non-Tuberculous Mycobacteria Infection in Bronchiectasis [J].
Faverio, Paola ;
Stainer, Anna ;
Bonaiti, Giulia ;
Zucchetti, Stefano C. ;
Simonetta, Edoardo ;
Lapadula, Giuseppe ;
Marruchella, Almerico ;
Gori, Andrea ;
Blasi, Francesco ;
Codecasa, Luigi ;
Pesci, Alberto ;
Chalmers, James D. ;
Loebinger, Michael R. ;
Aliberti, Stefano .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 17 (11)
[2]   An official ATS/IDSA statement: Diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases [J].
Griffith, David E. ;
Aksamit, Timothy ;
Brown-Elliott, Barbara A. ;
Catanzaro, Antonino ;
Daley, Charles ;
Gordin, Fred ;
Holland, Steven M. ;
Horsburgh, Robert ;
Huitt, Gwen ;
Iademarco, Michael F. ;
Iseman, Michael ;
Olivier, Kenneth ;
Ruoss, Stephen ;
von Reyn, C. Fordham ;
Wallace, Richard J., Jr. ;
Winthrop, Kevin .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2007, 175 (04) :367-416
[3]   Pulmonary disease by non-tuberculous mycobacteria - clinical management, unmet needs and future perspectives [J].
Larsson, Lars-Olof ;
Polverino, Eva ;
Hoefsloot, Wouter ;
Codecasa, Luigi R. ;
Diel, Roland ;
Jenkins, Stephen G. ;
Loebinger, Michael R. .
EXPERT REVIEW OF RESPIRATORY MEDICINE, 2017, 11 (12) :977-989
[4]  
Mencarini J, 2017, EPIDEMIOL INFECT, V145, P515, DOI [10.1017/S0950268816002521, 10.1017/s0950268816002521]
[5]  
Rindi L, BMC INFECT DIS
[6]   Macrolide/Azalide Therapy for Nodular/Bronchiectatic Mycobacterium avium Complex Lung Disease [J].
Wallace, Richard J., Jr. ;
Brown-Elliott, Barbara A. ;
McNulty, Steven ;
Philley, Julie V. ;
Killingley, Jessica ;
Wilson, Rebecca W. ;
York, Deanna S. ;
Shepherd, Sara ;
Griffith, David E. .
CHEST, 2014, 146 (02) :276-282
[7]   Treatment outcomes for Mycobacterium avium complex: a systematic review and meta-analysis [J].
Xu, H. -B. ;
Jiang, R. -H. ;
Li, L. .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2014, 33 (03) :347-358