In silico genome-wide screening for TnrA-regulated genes of Bacillus clausii

被引:0
作者
Farazmand, Abbas [1 ,2 ]
Yakhchali, Bagher [1 ]
Shariati, Parvin [1 ]
Minuchehr, Zarrin [1 ]
Ofoghi, Hamideh [2 ]
机构
[1] NIGEB, Dept Ind & Environm Biotechnol, Tehran, Iran
[2] IROST, Dept Biotechnol, Tehran, Iran
关键词
Gene regulation; TnrA; Bacillus clausii; nitrogen metabolism; SUBTILIS; EXPRESSION;
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Bacillus clausii TnrA transcription factor is required for global nitrogen regulation. In order to obtain an overview of gene regulation by TnrA in B. clausii KSM-K16, the entire genome of B. clausii was screened for the consensus sequence, 5'-TGTNAN7TNACA-3' known as the TnrA box, and 13 transcription units were found containing a putative TnrA box. The TnrA targets identified in this study were tnrA, glnA, nrgA, nasFDEB, puc genes, licT, the two operons of the oligopeptide ABC transporter, lytR, transcriptional regulator of the Lrp/AsnC family, sodium-dependent transporter of SNF family, hyu genes and a biochemically uncharacterized protein.
引用
收藏
页码:61 / 65
页数:5
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