Use of tocilizumab, remdesivir, and high-dose methylprednisolone prevents intubation in an ESRD patient with COVID-19 pneumonia

被引：4

作者：

Judge, Ramzan ^{[1
]}

Kolaski, Stephanie ^{[2
]}

Qadeer, Farhan ^{[1
]}

机构：

[1] Shore Med Ctr, 100 Med Ctr Way, Somers Point, NJ 08244 USA

[2] Thomas Jefferson Univ, Jefferson Coll Pharm, Philadelphia, PA 19107 USA

来源：

SAGE OPEN MEDICAL CASE REPORTS | 2022年 / 10卷

关键词：

Critical care/emergency medicine; nephrology; infectious diseases; COVID-19; steroids; remdesivir; tocilizumab; end-stage renal disease;

D O I：

10.1177/2050313X211069023

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Coronavirus disease 2019 (COVID-19) has affected over 200 million patients worldwide. COVID-19 is transmitted through respiratory droplets from patient to patient or by touching a surface that has been contaminated by an infected patient. Many COVID-19 patients have other comorbidities, such as end-stage renal disease. Currently, management of COVID-19 in patients with end-stage renal disease is unclear. Some studies have shown improvement in this population with the use of tocilizumab, a humanized interleukin-6 monoclonal antibody, in addition to the standard therapy as per guidelines published by the National Institutes of Health. In this case report, we present a patient case where the use of remdesivir, tocilizumab, and pulse-dose methylprednisolone significantly improved symptoms and inflammatory biomarkers associated with COVID-19 in a patient with end-stage renal disease.

引用

页数：5

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