Modeling biofilm processes using the immersed boundary method

被引:111
作者
Dillon, R
Fauci, L
Fogelson, A
Gaver, D
机构
[1] UNIV UTAH,DEPT MATH,SALT LAKE CITY,UT 84102
[2] TULANE UNIV,DEPT BIOMED ENGN,NEW ORLEANS,LA 70118
关键词
D O I
10.1006/jcph.1996.0233
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Biofilm processes are of interest to researchers in a variety of fields including bioremediation, oil recovery, wastewater treatment, medicine, and dentistry. In this paper we describe how this complex, dynamic, fluid-structure interaction can be modeled successfully using the immersed boundary method. The model presented here includes the coupling of hydrodynamics; substrate reaction, diffusion, and convection; as well as the chemotactic response of swimming microbes. Cell-cell aggregation and cell-substratum adhesion are modeled by generating appropriate binding forces between discrete representations of organisms that may hold them together, or ii fluid stresses are large, may yield and release the organisms. In this paper, we show two-dimensional numerical simulations to demonstrate several different types of scenarios that may be modeled using immersed boundary methods. These simulations indicate the variety of different phenomena one might expect in biofilm processes. (C) 1996 Academic Press, Inc.
引用
收藏
页码:57 / 73
页数:17
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