Feasibility and construct validity of a Frailty index for patients with chronic kidney disease

被引：42

作者：

Hubbard, Ruth E. ^{[1
]}

Peel, Nancye M. ^{[1
]}

Smith, Morgan ^{[2
,3
]}

Dawson, Blake ^{[3
]}

Lambat, Zahed ^{[3
]}

Bak, Melissa ^{[3
]}

Best, Jennifer ^{[4
]}

Johnson, David W. ^{[4
]}

机构：

[1] Univ Queensland, Ctr Res Geriatr Med, Brisbane, Qld, Australia

[2] Ochsner Med Sch, New Orleans, LA USA

[3] Univ Queensland, Sch Med, Brisbane, Qld, Australia

[4] Univ Queensland, Dept Nephrol, Brisbane, Qld, Australia

来源：

AUSTRALASIAN JOURNAL ON AGEING | 2015年 / 34卷 / 03期

关键词：

chronic kidney disease; Frailty index; Fried Frailty; COMPREHENSIVE GERIATRIC ASSESSMENT; PHYSICAL FUNCTION; DIALYSIS; ASSOCIATION; MORTALITY;

D O I：

10.1111/ajag.12231

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

AimTo determine whether the frailty status of patients with chronic kidney disease (CKD) can be measured using a Frailty index (FI). MethodsOne hundred and eleven attending a nephrology clinic were approached to complete a one-page questionnaire evaluating cognitive, psychological and functional status. Data were coded as deficits, summed and divided by the total number of deficits considered, to derive an FI-CKD. ResultsOne hundred and ten (mean age 65.2 years) agreed to participate and assessments took approximately 10 minutes to complete. Mean FI-CKD was 0.25 (SD 0.12). The FI-CKD increased with age at 3% per year, correlated with a modified Fried phenotype (P < 0.001) and increased significantly across CKD stages (P = 0.04). ConclusionsThe FI-CKD is feasible in the outpatient setting and has good construct validity. The greater granularity of a continuous measure has the potential to inform decision-making regarding appropriate interventions for patients at the frail' end of the health spectrum.

引用

页码：E9 / E12

页数：4

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