Smart multifunctional polyurethane microcapsules for the quick release of anticancer drugs in BGC 823 and HeLa tumor cells

被引：57

作者：

Niu, Yuqing ^{[1
,2
]}

Stadler, Florian J. ^{[1
]}

He, Tao ^{[3
]}

Zhang, Xingcai ^{[4
]}

Yu, Yingjie ^{[5
]}

Chen, Shiguo ^{[1
]}

机构：

[1] Shenzhen Univ, Nanshan Dist Key Lab Biopolymers & Safety Evaluat, Shenzhen Key Lab Polymer Sci & Technol, Guangdong Res Ctr Interfacial Engn Funct Mat,Coll, Shenzhen 518060, Peoples R China

[2] Shenzhen Univ, Key Lab Optoelect Devices & Syst, Minist Educ & Guangdong Prov, Coll Optoelect Engn, Shenzhen 518060, Peoples R China

[3] Shantou Univ, Multidisciplinary Res Ctr, Shantou 515063, Guangdong, Peoples R China

[4] Sun Yat Sen Univ, Inst Mat Sci, Guangzhou 510275, Guangdong, Peoples R China

[5] SUNY Stony Brook, Dept Mat Sci & Engn, Stony Brook, NY 11794 USA

来源：

JOURNAL OF MATERIALS CHEMISTRY B | 2017年 / 5卷 / 48期

基金：

中国国家自然科学基金;

关键词：

AGGREGATION-INDUCED EMISSION; OVERCOMING MULTIDRUG-RESISTANCE; DELIVERY; CANCER; NANOPARTICLES; BIODISTRIBUTION; FABRICATION; BLEOMYCIN; COPOLYMER; POLYMERS;

D O I：

10.1039/c7tb02570j

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Smart multifunctional drug delivery systems (DDSs) based on cytophilic fluorescent polyurethane copolymer microcapsules with high tumor cell internalization, triggered release, quick cancer cell death and real time fluorescent monitoring abilities is developed as a facile and versatile approach for precision cancer therapy.

引用

页码：9477 / 9481

页数：5

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