A biointerface effect on the self-assembly of ribonucleic acids: a possible mechanism of RNA polymerisation in the self-replication cycle

被引:11
作者
Arai, Noriyoshi [1 ]
Kobayashi, Yusei [1 ]
Yasuoka, Kenji [1 ]
机构
[1] Keio Univ, Dept Engn, Yokohama, Kanagawa 2238522, Japan
关键词
DISSIPATIVE PARTICLE DYNAMICS; BROWNIAN MOTOR DRIVEN; FLIP-FLOP; NANOPARTICLE TRANSLOCATION; JANUS; MODEL; CELL; CONFORMATION; SIMULATION; BEHAVIORS;
D O I
10.1039/c9nr09537c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Despite decades of intensive research, many questions remain on the formation and growth of the first cells on Earth. Here, we used computer simulation to compare the self-assembly process of ribonucleic acids in two environments: enclosed in a vesicle-cell membrane and in the bulk. The self-assembly was found to be more favoured in the former environment, and the origin of such a biointerface effect was identified. These results will contribute to a better understanding of the origin of life on the primitive Earth.
引用
收藏
页码:6691 / 6698
页数:8
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