Novel approaches combining native electrospray ionization with ion mobility-mass spectrometry provide access to structural information for large and dynamic, even heterogeneous assemblies of biomolecules. In this short review we will investigate these methods and highlight some recent applications for proteins and protein complexes.
机构:
Institutes of Biomedical Sciences, Department of Chemistry, Fudan University, ShanghaiInstitutes of Biomedical Sciences, Department of Chemistry, Fudan University, Shanghai
Fu B.
Liang Y.-Y.
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机构:
Institutes of Biomedical Sciences, Department of Chemistry, Fudan University, ShanghaiInstitutes of Biomedical Sciences, Department of Chemistry, Fudan University, Shanghai
Liang Y.-Y.
Lu H.-J.
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机构:
Institutes of Biomedical Sciences, Department of Chemistry, Fudan University, Shanghai
NHC Key Laboratory of Glycoconjugates Research, Fudan University, ShanghaiInstitutes of Biomedical Sciences, Department of Chemistry, Fudan University, Shanghai