Hybrid Myxoinflammatory Fibroblastic Sarcoma/Hemosiderotic Fibrolipomatous Tumor: Report of a Case Providing Further Evidence for a Pathogenetic Link

被引：39

作者：

Elco, Christopher P. ^{[1
]}

Marino-Enriquez, Adrian ^{[1
,3
]}

Abraham, John A. ^{[2
]}

Dal Cin, Paola ^{[1
]}

Hornick, Jason L. ^{[1
]}

机构：

[1] Harvard Univ, Dept Pathol, Sch Med, Brigham & Womens Hosp, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Dana Farber Canc Inst, Ctr Bone & Sarcoma Oncol, Boston, MA 02115 USA

[3] Univ Autonoma Madrid, Hosp Univ La Paz, Dept Anat Patol, Madrid, Spain

来源：

AMERICAN JOURNAL OF SURGICAL PATHOLOGY | 2010年 / 34卷 / 11期

关键词：

myxoinflammatory fibroblastic sarcoma; hemosiderotic fibrolipomatous tumor; t(1; 10); cytogenetics; low-grade sarcoma; soft tissue tumor; FIBROHISTIOCYTIC LIPOMATOUS LESION; HYALINIZING ANGIECTATIC TUMOR; MYXOHYALINE TUMOR; SARCOMA; CELLS;

D O I：

10.1097/PAS.0b013e3181f17d51

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Myxoinflammatory fibroblastic sarcoma and hemosiderotic fibrolipomatous tumor are rare, slow-growing soft tissue tumors of the distal extremities with recurrent potential. Recent cytogenetic studies have shown a t(1;10)(p22;q24) or der(10) t(1;10) in combination with aberrations of chromosome 3 in a limited number of cases of both entities. Here we report a case of a 42-year-old female with a soft tissue tumor of the ankle showing hybrid morphologic features of myxoinflammatory fibroblastic sarcoma and hemosiderotic fibrolipomatous tumor, a der(10) t(1;10), and abnormalities of chromosome 3. This hybrid lesion provides further evidence for a close relationship between these 2 tumor types.

引用

页码：1723 / 1727

页数：5

共 16 条

[1] Myxoinflammatory fibroblastic sarcoma:: investigations by comparative genomic hybridization of two cases and review of the literature [J].

Baumhoer, Daniel ;

Glatz, Kathrin ;

Schulten, Hans-Juergen ;

Fuezesi, Laszlo ;

Fricker, Renato ;

Kettelhack, Christoph ;

Hasenboehler, Paula ;

Oberholzer, Martin ;

Jundt, Gernot .

VIRCHOWS ARCHIV, 2007, 451 (05) :923-928

[2] Haemosiderotic fibrolipomatous tumour (so-called haemosiderotic fibrohistiocytic lipomatous tumour): analysis of 13 new cases in support of a distinct entity [J].

Browne, TJ ;

Fletcher, CDM .

HISTOPATHOLOGY, 2006, 48 (04) :453-461

[3] Pleomorphic hyalinizing angiectatic tumor - Analysis of 41 cases supporting evolution from a distinctive precursor lesion [J].

Folpe, AL ;

Weiss, SW .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2004, 28 (11) :1417-1425

[4] Fine needle aspiration cytology of an acral myxoinflammatory fibroblastic sarcoma:: case report with cytological and cytogenetic findings [J].

Gonzalez-Campora, R. ;

Rios-Martin, J. J. ;

Solorzano-Amoretti, A. ;

Monteros, M. T. Vargas de Los ;

Trigo-Sanchez, I. ;

Otal-Salaverri, C. ;

Galera-Davidson, H. .

CYTOPATHOLOGY, 2008, 19 (02) :118-123

[5] Two genetic pathways, t(1;10) and amplification of 3p11-12, in myxoinflammatory fibroblastic sarcoma, haemosiderotic fibrolipomatous tumour, and morphologically similar lesions [J].

Hallor, Karolin H. ;

Sciot, Raf ;

Staaf, Johan ;

Heidenblad, Markus ;

Rydholm, Anders ;

Bauer, Henrik C. F. ;

Astrom, Kristina ;

Domanski, Henryk A. ;

Meis, Jeanne M. ;

Kindblom, Lars-Gunnar ;

Panagopoulos, Ioannis ;

Mandahl, Nils ;

Mertens, Fredrik .

JOURNAL OF PATHOLOGY, 2009, 217 (05) :716-727

[6] Myxoinflammatory fibroblastic sarcoma showing t(2;6)(q31;p21.3) as a sole cytogenetic abnormality [J].

Ida, Cristiane M. ;

Rolig, Kristen A. ;

Hulshizer, Rachael L. ;

Van Dyke, Daniel L. ;

Randolph, Jamie L. ;

Jenkins, Robert B. ;

Nascimento, Antonio G. ;

Oliveira, Andre M. .

CANCER GENETICS AND CYTOGENETICS, 2007, 177 (02) :139-142

[7] Acral myxoinflammatory fibroblastic sarcoma with unique clonal chromosomal changes [J].

Lambert, I ;

Debiec-Rychter, M ;

Guelinckx, P ;

Hagemeijer, A ;

Sciot, R .

VIRCHOWS ARCHIV, 2001, 438 (05) :509-512

[8] Hemosiderotic fibrohistiocytic lipomatous lesion: Early pleomorphic hyalinizing angiectatic tumor? [J].

Luzar, B ;

Gasljevic, G ;

Juricic, V ;

Bracko, M .

PATHOLOGY INTERNATIONAL, 2006, 56 (05) :283-286

[9] Myxoinflammatory fibroblastic sarcoma with complex supernumerary ring chromosomes composed of chromosome 3 segments [J].

Mansoor, A ;

Fidda, N ;

Himoe, E ;

Payne, M ;

Lawce, H ;

Magenis, RE .

CANCER GENETICS AND CYTOGENETICS, 2004, 152 (01) :61-65

[10] Hemosiderotic fibrohistiocytic lipomatous lesion: Ten cases of a previously undescribed fatty lesion of the foot/ankle [J].

Marshall-Taylor, C ;

Fanburg-Smith, JC .

MODERN PATHOLOGY, 2000, 13 (11) :1192-1199

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