Increased Neutrophil to Lymphocyte Ratio in Patients With Resistant Hypertension

被引：52

作者：

Belen, Erdal ^{[1
]}

Sungur, Aylin ^{[2
]}

Sungur, Mustafa Azmi ^{[2
]}

Erdogan, Guney ^{[3
]}

机构：

[1] Okmeydan Training & Res Hosp, Dept Cardiol, Istanbul, Turkey

[2] Kahramanmaras Necip Fazl City Hosp, Dept Cardiol, Kahramanmaras, Turkey

[3] Ordu Training & Res Hosp, Dept Cardiol, Ordu, Turkey

来源：

JOURNAL OF CLINICAL HYPERTENSION | 2015年 / 17卷 / 07期

关键词：

C-REACTIVE PROTEIN; BLOOD-CELL COUNT; LEUKOCYTE COUNT; NEUTROPHIL/LYMPHOCYTE RATIO; SYSTEMIC INFLAMMATION; MYOCARDIAL-INFARCTION; RISK-FACTORS; ASSOCIATION; PREDICTOR; PRESSURE;

D O I：

10.1111/jch.12533

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Resistant hypertension (RHT) is an important disease that causes an increase in cardiovascular risk, yet its etiology remains unclear. The authors aimed to investigate neutrophil/lymphocyte ratio (NLR) as an inflammation marker in patients with RHT. A total of 150 patients were included in the study and grouped according to their office and ambulatory blood pressure measurements. They were classified as having normotension (NT), controlled hypertension (CHT), or RHT. The RHT group had a significantly higher NLR than the CHT group (P=.03), and NLRs of both hypertension groups were significantly higher than those in the NT group (P<.001, for both). NLR and neutrophil count were found to be independent correlates for RHT in multivariate analysis (P<.001). NLR and neutrophil count are increased in RHT patients than both CHT and NT patients. This finding, which is defined for the first time in patients with RHT, may imply the importance of inflammation in blood pressure control. (C) 2015 Wiley Periodicals, Inc.

引用

页码：532 / 537

页数：6

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