Outbreak Size Distribution in Stochastic Epidemic Models

被引:14
作者
Hindes, Jason [1 ]
Assaf, Michael [2 ,3 ]
Schwartz, Ira B. [1 ]
机构
[1] US Naval Res Lab, Washington, DC 20375 USA
[2] Hebrew Univ Jerusalem, Racah Inst Phys, IL-91904 Jerusalem, Israel
[3] Univ Potsdam, Inst Phys & Astron, D-14476 Potsdam, Germany
基金
以色列科学基金会;
关键词
D O I
10.1103/PhysRevLett.128.078301
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
Motivated by recent epidemic outbreaks, including those of COVID-19, we solve the canonical problem of calculating the dynamics and likelihood of extensive outbreaks in a population within a large class of stochastic epidemic models with demographic noise, including the susceptible-infected-recovered (SIR) model and its general extensions. In the limit of large populations, we compute the probability distribution for all extensive outbreaks, including those that entail unusually large or small (extreme) proportions of the population infected. Our approach reveals that, unlike other well-known examples of rare events occurring in discrete-state stochastic systems, the statistics of extreme outbreaks emanate from a full continuum of Hamiltonian paths, each satisfying unique boundary conditions with a conserved probability flux.
引用
收藏
页数:6
相关论文
共 45 条
[41]   Outbreak statistics and scaling laws for externally driven epidemics [J].
Singh, Sarabjeet ;
Myers, Christopher R. .
PHYSICAL REVIEW E, 2014, 89 (04)
[42]   Quantifying asymptomatic infection and transmission of COVID-19 in New York City using observed cases, serology, and testing capacity [J].
Subramanian, Rahul ;
He, Qixin ;
Pascual, Mercedes .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 118 (09)
[43]   Explicit formulae for the peak time of an epidemic from the SIR model [J].
Turkyilmazoglu, Mustafa .
PHYSICA D-NONLINEAR PHENOMENA, 2021, 422
[44]   Multitype branching and graph product theory of infectious disease outbreaks [J].
Vazquez, Alexei .
PHYSICAL REVIEW E, 2021, 103 (03)
[45]   Forecasting Elections Using Compartmental Models of Infection [J].
Volkening, Alexandria ;
Linder, Daniel F. ;
Porter, Mason A. ;
Rempala, Grzegorz A. .
SIAM REVIEW, 2020, 62 (04) :837-865