HIV prevention metrics: lessons to be learned from contraception

被引:4
|
作者
Pyra, Maria [1 ]
Heffron, Renee [2 ]
Haberer, Jessica E. [3 ]
Kiarie, James [4 ]
机构
[1] Univ Chicago, Chicago, IL 60637 USA
[2] Univ Washington, Seattle, WA 98195 USA
[3] Massachusetts Gen Hosp, Boston, MA 02114 USA
[4] WHO, Geneva, Switzerland
关键词
HIV care continuum; HIV prevention; key and vulnerable populations; PrEP; adherence; retention; PREEXPOSURE PROPHYLAXIS; NATIONAL COHORT; PREP CASCADE; FRAMEWORK;
D O I
10.1002/jia2.25958
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Introduction As the range of effective HIV prevention options, including multiple biomedical tools, increases, there are many challenges to measuring HIV prevention efforts. In part, there is the challenge of varying prevention needs, between individuals as well as within individuals over time. The field of contraception faces many similar challenges, such as the range of prevention methods and changing contraceptive needs, and has developed many metrics for assessing contraceptive use at the program level, using frameworks that move beyond the HIV prevention cascade. We explore these similarities and differences between these two prevention fields and then discuss how each of these contraceptive metrics could be adapted to assessing HIV prevention. Discussion We examined measures of initiation, coverage and persistence. Among measures of initiation, HIV Prevention-Post Testing would be a useful corollary to Contraceptive Use-Post Partum for a subset of the population. As a measure of coverage, both Net Prevention Coverage and HIV Protection Index (modelled off the Contraception Protection Index) may be useful. Finally, as a measure of persistence, Person-Years of HIV Protection could be adapted from Couple-Years Protection. As in contraception, most programs will not reach 100% on HIV prevention metrics but these metrics are highly useful for making comparisons. Conclusions While we may not be able to perfectly capture the true population of who would benefit from HIV prevention, by building off the work of the contraceptive field to use and refine these metrics, we can assess and compare HIV prevention over time and across programs. Furthermore, these metrics can help us reach global targets, such as the 2025 UNAIDS Goals, and reduce HIV incidence.
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页数:6
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