Polarographic determination of metronidazole in pharmaceutical formulations and urine

被引：35
作者：
ElSayed, GO
机构：
[1] Chemistry Department, Faculty of Science, Benha University, Benha
来源：
MICROCHEMICAL JOURNAL | 1997年 / 55卷 / 01期
关键词：
D O I：
10.1006/mchj.1996.1307
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The dc polarographic behavior of metronidazole is studied in McIlvaine buffers. The reduction is irreversible and exhibits two waves; the first is suitable for analytical purposes. The limiting current shows a linear dependence with the drug concentration in the range 0.02-1 mM. A new polarographic method is examined for determination of metionidazole in commercial tablets and human urine. (C) 1997 Academic Press.
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收藏
页码：110 / 114
页数：5
相关论文
共 14 条
[1]  
ABUZUHRI AZ, 1986, ANAL LETT, V19, P453
[2]  
BARNES AR, 1985, J PHARM PHARMACOL, V37, P10
[3]  
BERTRAN GK, 1992, BASIC CLIN PHARM MID, P473
[4]  
BODINI ME, 1990, B ELECTROCHEM, V6, P802
[5]  
FAITH L, 1979, FARM POL, V35, P541
[6]  
KUBOTA M, 1982, GIFU YAKKA DAIGAKU K, V31, P29
[7]  
LIANG Y, 1994, FENXI CESHI XUEBAO, V13, P61
[8]  
Meites L., 1965, Polarographic Techniques
[9]   DETERMINATION OF METRONIDAZOLE IN TABLET FORMULATIONS BY DIFFERENTIAL PULSE POLAROGRAPHY [J].
PAPAS, AN ;
DELANEY, MF .
ANALYTICAL LETTERS PART B-CLINICAL AND BIOCHEMICAL ANALYSIS, 1982, 15 (08) :739-745
[10]  
SANKAR PS, 1990, ASIAN J CHEM, V2, P245
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