Detection of protein-protein interactions in vivo based on protein splicing

被引：39
|
作者：
Ozawa, T [1 ]
Umezawa, Y
机构：
[1] Univ Tokyo, Sch Sci, Dept Chem, Bunkyo Ku, Tokyo 1130033, Japan
[2] Japan Sci & Technol Corp, Tokyo, Japan
来源：
CURRENT OPINION IN CHEMICAL BIOLOGY | 2001年 / 5卷 / 05期
基金：
日本科学技术振兴机构;
关键词：
D O I：
10.1016/S1367-5931(00)00244-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In mammalian cells, protein-protein interactions constitute essential regulatory steps that modulate the activity of signaling pathways. In recent years, several approaches towards understanding the interactions have been developed. We describe herein a new method for detecting protein-protein interactions in vivo based on protein splicing and highlight some potential applications of this technique.
引用
收藏
页码：578 / 583
页数：6
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