Label-free photoacoustic imaging of human palmar vessels: a structural morphological analysis

被引：65

作者：

Matsumoto, Y. ^{[1
]}

Asao, Y. ^{[1
]}

Yoshikawa, A. ^{[1
]}

Sekiguchi, H. ^{[2
]}

Takada, M. ^{[1
]}

Furu, M. ^{[3
]}

Saito, S. ^{[4
]}

Kataoka, M. ^{[2
]}

Abe, H. ^{[6
]}

Yagi, T. ^{[5
]}

Togashi, K. ^{[2
]}

Toi, M. ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Med, Dept Breast Surg, Sakyo Ku, 54 Shogoin Kawaharacho, Kyoto 6068507, Japan

[2] Kyoto Univ, Grad Sch Med, Dept Diagnost Imaging & Nucl Med, Sakyo Ku, 54 Shogoin Kawaharacho, Kyoto 6068507, Japan

[3] Kyoto Univ, Grad Sch Med, Dept Orthopaed Surg, Sakyo Ku, 54 Shogoin Kawaharacho, Kyoto 6068507, Japan

[4] Kyoto Univ, Grad Sch Med, Dept Plast & Reconstruct Surg, Sakyo Ku, 53 Shogoin Kawaharacho, Kyoto 6068507, Japan

[5] Japan Sci & Technol Agcy, Cabinet Off, imPACT Program, Chiyoda Ku, Ks Gobancho 7, Tokyo 1020076, Japan

[6] Canon Inc, Med Imaging Syst Dev Ctr, Ohta Ku, 3-30-2 Shimomaruko, Tokyo 1468501, Japan

来源：

SCIENTIFIC REPORTS | 2018年 / 8卷

关键词：

D O I：

10.1038/s41598-018-19161-z

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We analysed the vascular morphology of the palm using a photoacoustic tomography (PAT) instrument with a hemispherical detector array. The three-dimensional (3D) morphology of blood vessels was determined noninvasively. Overall, 12 females and 11 males were recruited as healthy volunteers. Their ages were distributed almost evenly from 22 to 59 years. In all cases, many vascular networks were observed just beneath the skin and were determined to be veins anatomically. To analyse the major arteries, the layer containing the subcutaneous venous network was removed from the image. The analysis focused on the common and proper palmar digital arteries. We used the curvature of these arteries as a parameter to analyse their morphologies. There was no significant difference in the curvature between genders when comparing the subjects as a whole. The blood vessel curvature increased with age. Good agreement was found between the 3D numerical analysis results and the subjective evaluation of the two-dimensional (2D) projection image. The PAT system enabled visualization of the 3D features of blood vessels in the palm and noninvasive analysis of arterial tortuousness.

引用

页数：8

共 22 条

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