A novel method for estimating the adaptive ability of guide dogs using salivary sIgA

被引:28
作者
Kikkawa, A
Uchida, Y
Suwa, Y
Taguchi, K
机构
[1] Rakuno Gakuen Univ, Sch Vet Med, Ebetsu, Hokkaido 0698501, Japan
[2] Hokkaido Guide Dogs Blin Assoc, Minami Ku, Sapporo, Hokkaido 0058222, Japan
关键词
canine; guide dog; saliva; sIgA; stress;
D O I
10.1292/jvms.67.707
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Salivary secretory immunoglobulin A (slgA) concentrations of prospective guide dogs for the blind were determined to clarify whether salivary slgA is useful in evaluating the potential suitability of guide dogs for the blind. Saliva was collected from 73 prospective guide dogs in the kennel on day 1 (the day of separation from volunteer puppy-raisers), 2, 3, 7 and 14 during the estimation period (at about 1 year old). We selected particularly suitable dogs (superior dogs) and unsuitable dogs (inferior dogs) on the basis of the trainers' estimation. All dogs were divided into two groups, those were acceptable dogs would become the guide dogs and rejected dogs could not become guide dogs. The slgA concentrations in superior dogs gradually increased from day 1 to 14 and those in inferior dogs remained at low levels. Moreover, the slgA concentrations on day 14 in the acceptable dogs were significantly higher than those in rejected dogs. The cut-off point of slgA concentrations on day 14 using an ROC curve was 90 EU/ml, and the specificity of the estimation at this point (70.4%) was higher than that of trainers' estimation (50%). Moreover, parallel testing using both trainers' estimation and slgA estimation, showed that specificity was further improved (79.5%). The present study showed that slgA concentration was extremely useful in estimating the adaptive ability for guide dogs for the blind.
引用
收藏
页码:707 / 712
页数:6
相关论文
共 23 条
[1]   Dynamics of stress-related decrease of salivary immunoglobulin A (sIgA): Relationship to symptoms of the common cold and studying behavior [J].
Deinzer, R ;
Schuller, N .
BEHAVIORAL MEDICINE, 1998, 23 (04) :161-169
[2]   Prolonged reduction of salivary immunoglobulin A (sIgA) after a major academic exam [J].
Deinzer, R ;
Kleineidam, C ;
Stiller-Winkler, R ;
Idel, H ;
Bachg, D .
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, 2000, 37 (03) :219-232
[3]  
DODDARD ME, 1984, APPL ANIM BEHAV SCI, V12, P253
[4]   Social class, sex, and age differences in mucosal immunity in a large community sample [J].
Evans, P ;
Der, G ;
Ford, G ;
Hucklebridge, F ;
Hunt, K ;
Lambert, S .
BRAIN BEHAVIOR AND IMMUNITY, 2000, 14 (01) :41-48
[5]   GENETIC AND ENVIRONMENTAL-FACTORS AFFECTING THE SUITABILITY OF DOGS AS GUIDE DOGS FOR THE BLIND [J].
GODDARD, ME ;
BEILHARZ, RG .
THEORETICAL AND APPLIED GENETICS, 1982, 62 (02) :97-102
[6]   DOES ANXIETY REDUCE THE SECRETION RATE OF SECRETORY IGA IN SALIVA [J].
GRAHAM, NMH ;
BARTHOLOMEUSZ, RCA ;
TABOONPONG, N ;
LABROOY, JT .
MEDICAL JOURNAL OF AUSTRALIA, 1988, 148 (03) :131-133
[7]  
HENNINGSEN GM, 1992, SCAND J WORK ENV HEA, V18, P133
[8]   The relationship between salivary secretory immunoglobulin A and cortisol: neuroendocrine response to awakening and the diurnal cycle [J].
Hucklebridge, F ;
Clow, A ;
Evans, P .
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, 1998, 31 (01) :69-76
[9]   Modulation of secretory immunoglobulin A in saliva; response to manipulation of mood [J].
Hucklebridge, F ;
Lambert, S ;
Clow, A ;
Warburton, DM ;
Evans, PD ;
Sherwood, N .
BIOLOGICAL PSYCHOLOGY, 2000, 53 (01) :25-35
[10]  
Kikkawa A, 2003, J VET MED SCI, V65, P689, DOI 10.1292/jvms.65.689