Low mean post-transplantation tacrolimus levels in weeks 2-3 correlate with acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation from related and unrelated donors

被引：11
作者：
Hagen, Patrick A. [1 ]
Adams, William [2 ]
Smith, Scott [3 ]
Tsai, Stephanie [1 ]
Stiff, Patrick [3 ]
机构：
[1] Loyola Univ Med Ctr, Internal Med, Maywood, IL 60153 USA
[2] Loyola Univ, Clin Res Off Biostat Core, Maywood, IL 60153 USA
[3] Loyola Univ Med Ctr, Hematol Oncol, Maywood, IL 60153 USA
来源：
BONE MARROW TRANSPLANTATION | 2019年 / 54卷 / 01期
关键词：
PROPHYLAXIS; RISK; CYCLOSPORINE; INDEX; BLOOD; GVHD;
D O I：
10.1038/s41409-018-0267-5
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
引用
收藏
页码：155 / 158
页数：4
相关论文
共 14 条
  • [1] A disease risk index for patients undergoing allogeneic stem cell transplantation
    Armand, Philippe
    Gibson, Christopher J.
    Cutler, Corey
    Ho, Vincent T.
    Koreth, John
    Alyea, Edwin P.
    Ritz, Jerome
    Sorror, Mohamed L.
    Lee, Stephanie J.
    Deeg, H. Joachim
    Storer, Barry E.
    Appelbaum, Frederick R.
    Antin, Joseph H.
    Soiffer, Robert J.
    Kim, Haesook T.
    [J]. BLOOD, 2012, 120 (04) : 905 - 913
  • [2] Higher tacrolimus concentrations early after transplant reduce the risk of acute GvHD in reduced-intensity allogeneic stem cell transplantation
    Ganetsky, A.
    Shah, A.
    Miano, T. A.
    Hwang, W-T
    He, J.
    Loren, A. W.
    Hexner, E. O.
    Frey, N. V.
    Porter, D. L.
    Reshef, R.
    [J]. BONE MARROW TRANSPLANTATION, 2016, 51 (04) : 568 - 572
  • [3] Phase III study comparing tacrolimus (FK506) with cyclosporine for graft-versus-host disease prophylaxis after allogeneic bone marrow transplantation
    Hiraoka, A
    Ohashi, Y
    Okamoto, S
    Moriyama, Y
    Nagao, T
    Kodera, Y
    Kanamaru, A
    Dohy, H
    Masaoka, T
    [J]. BONE MARROW TRANSPLANTATION, 2001, 28 (02) : 181 - 185
  • [4] FK-506, A NOVEL IMMUNOSUPPRESSANT ISOLATED FROM A STREPTOMYCES .1. FERMENTATION, ISOLATION, AND PHYSICOCHEMICAL AND BIOLOGICAL CHARACTERISTICS
    KINO, T
    HATANAKA, H
    HASHIMOTO, M
    NISHIYAMA, M
    GOTO, T
    OKUHARA, M
    KOHSAKA, M
    AOKI, H
    IMANAKA, H
    [J]. JOURNAL OF ANTIBIOTICS, 1987, 40 (09) : 1249 - 1255
  • [5] Effect of Early Posttransplantation Tacrolimus Concentration on the Development of Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation from Unrelated Donors
    Mori, Takehiko
    Kato, Jun
    Shimizu, Takayuki
    Aisa, Yoshinobu
    Nakazato, Tomonori
    Yamane, Akiko
    Ono, Yukako
    Kunimoto, Hiroyoshi
    Okamoto, Shinichiro
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2012, 18 (02) : 229 - 234
  • [6] Pasquini MC., 2015, CIBMTR Summary Slides
  • [7] Tacrolimus does not abrogate the increased risk of acute graft-versus-host disease after unrelated-donor marrow transplantation with allelic mismatching at HLA-DRB I and HLA-DQB I
    Przepiorka, D
    Saliba, R
    Cleary, K
    Fischer, H
    Tonai, R
    Fritsche, H
    Khouri, IF
    Folloder, J
    Ueno, NT
    Mehra, R
    Ippoliti, C
    Giralt, S
    Gajewski, J
    Donato, M
    Claxton, D
    Braunschweig, I
    van Besien, K
    Anderlini, P
    Andersson, BS
    Champlin, R
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2000, 6 (2A) : 190 - 197
  • [8] Association between Calcineurin Inhibitor Blood Concentrations and Outcomes after Allogeneic Hematopoietic Cell Transplantation
    Ram, Ron
    Storer, Barry
    Mielcarek, Marco
    Sandmaier, Brenda M.
    Maloney, David G.
    Martin, Paul J.
    Flowers, Mary E. D.
    Chua, Bee K.
    Rotta, Marcello
    Storb, Rainer
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2012, 18 (03) : 414 - 422
  • [9] Ratanatharathorn V, 1998, BLOOD, V92, P2303
  • [10] IBMTR Severity Index for grading acute graft-versus-host disease: Retrospective comparison with Glucksberg grade
    Rowlings, PA
    Przepiorka, D
    Klein, JP
    Gale, RP
    Passweg, JR
    HensleeDowney, PJ
    Cahn, JY
    Calderwood, S
    Gratwohl, A
    Socie, G
    Abecasis, MM
    Sobocinski, KA
    Zhang, MJ
    Horowitz, MM
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 1997, 97 (04) : 855 - 864
12