GPR15: a tale of two species

被引：8
作者：
Bilsborough, Janine [1 ,2 ]
Viney, Joanne L. [3 ]
机构：
[1] Cedars Sinai Med Ctr, Fdn Inflammatory Bowel, Los Angeles, CA 90048 USA
[2] Cedars Sinai Med Ctr, Inst Immunobiol, Los Angeles, CA 90048 USA
[3] Biogen Idec Inc, Immunol Res, Cambridge, MA USA
来源：
NATURE IMMUNOLOGY | 2015年 / 16卷 / 02期
基金：
英国医学研究理事会;
关键词：
INDUCED COLITIS;
D O I：
10.1038/ni.3084
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The chemoattractant receptor GPR15 directs the homing of T cells to the colon; however, GRP15 expression differs in the effector and regulatory T cell subsets of humans versus those of mice. These findings have profound implications for the potential targeting of GRP15 for therapeutic intervention.
引用
收藏
页码：137 / 139
页数：3
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