EGFR Antibodies in Colorectal Cancer: Where Do They Belong?

被引:34
作者
Grothey, Axel [1 ]
机构
[1] Mayo Clin, Rochester, MN 55905 USA
关键词
PHASE-III TRIAL; 1ST-LINE TREATMENT; CETUXIMAB; PANITUMUMAB; FLUOROURACIL; BEVACIZUMAB; OXALIPLATIN; LEUCOVORIN; IRINOTECAN; CHEMOTHERAPY;
D O I
10.1200/JCO.2010.29.3407
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:4668 / 4670
页数:4
相关论文
共 18 条
  • [1] Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
    Amado, Rafael G.
    Wolf, Michael
    Peeters, Marc
    Van Cutsem, Eric
    Siena, Salvatore
    Freeman, Daniel J.
    Juan, Todd
    Sikorski, Robert
    Suggs, Sid
    Radinsky, Robert
    Patterson, Scott D.
    Chang, David D.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (10) : 1626 - 1634
  • [2] [Anonymous], J CLIN ONCOL S
  • [3] Biomarkers of Resistance to Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients with Metastatic Colorectal Cancer
    Banck, Michaela S.
    Grothey, Axel
    [J]. CLINICAL CANCER RESEARCH, 2009, 15 (24) : 7492 - 7501
  • [4] Fluorouracil, Leucovorin, and Oxaliplatin With and Without Cetuximab in the First-Line Treatment of Metastatic Colorectal Cancer
    Bokemeyer, Carsten
    Bondarenko, Igor
    Makhson, Anatoly
    Hartmann, Joerg T.
    Aparicio, Jorge
    de Braud, Filippo
    Donea, Serban
    Ludwig, Heinz
    Schuch, Gunter
    Stroh, Christopher
    Loos, Anja H.
    Zubel, Angela
    Koralewski, Piotr
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (05) : 663 - 671
  • [5] Randomized, Phase III Trial of Panitumumab With Infusional Fluorouracil, Leucovorin, and Oxaliplatin (FOLFOX4) Versus FOLFOX4 Alone As First-Line Treatment in Patients With Previously Untreated Metastatic Colorectal Cancer: The PRIME Study
    Douillard, Jean-Yves
    Siena, Salvatore
    Cassidy, James
    Tabernero, Josep
    Burkes, Ronald
    Barugel, Mario
    Humblet, Yves
    Bodoky, Gyoergy
    Cunningham, David
    Jassem, Jacek
    Rivera, Fernando
    Kocakova, Ilona
    Ruff, Paul
    Blasinska-Morawiec, Maria
    Smakal, Martin
    Canon, Jean-Luc
    Rother, Mark
    Oliner, Kelly S.
    Wolf, Michael
    Gansert, Jennifer
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (31) : 4697 - 4705
  • [6] Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial
    Folprecht, Gunnar
    Gruenberger, Thomas
    Bechstein, Wolf O.
    Raab, Hans-Rudolf
    Lordick, Florian
    Hartmann, Joerg T.
    Lang, Hauke
    Frilling, Andrea
    Stoehlmacher, Jan
    Weitz, Juergen
    Konopke, Ralf
    Stroszczynski, Christian
    Liersch, Torsten
    Ockert, Detlev
    Herrmann, Thomas
    Goekkurt, Eray
    Parisi, Fabio
    Koehne, Claus-Henning
    [J]. LANCET ONCOLOGY, 2010, 11 (01) : 38 - 47
  • [7] A Randomized Phase IIIB Trial of Chemotherapy, Bevacizumab, and Panitumumab Compared With Chemotherapy and Bevacizumab Alone for Metastatic Colorectal Cancer
    Hecht, J. Randolph
    Mitchell, Edith
    Chidiac, Tarek
    Scroggin, Carroll
    Hagenstad, Christopher
    Spigel, David
    Marshall, John
    Cohn, Allen
    McCollum, David
    Stella, Philip
    Deeter, Robert
    Shahin, Seta
    Amado, Rafael G.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (05) : 672 - 680
  • [8] K-ras mutations and benefit from cetuximab in advanced colorectal cancer
    Karapetis, Christos S.
    Khambata-Ford, Shirin
    Jonker, Derek J.
    O'Callaghan, Chris J.
    Tu, Dongsheng
    Tebbutt, Niall C.
    Simes, R. John
    Chalchal, Haji
    Shapiro, Jeremy D.
    Robitaille, Sonia
    Price, Timothy J.
    Shepherd, Lois
    Au, Heather-Jane
    Langer, Christiane
    Moore, Malcolm J.
    Zalcberg, John R.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (17) : 1757 - 1765
  • [9] MAUGHAN TS, 2010, J CLIN ONCOL S, V28, pS261
  • [10] Randomized Phase III Study of Panitumumab With Fluorouracil, Leucovorin, and Irinotecan (FOLFIRI) Compared With FOLFIRI Alone As Second-Line Treatment in Patients With Metastatic Colorectal Cancer
    Peeters, Marc
    Price, Timothy Jay
    Cervantes, Andres
    Sobrero, Alberto F.
    Ducreux, Michel
    Hotko, Yevhen
    Andre, Thierry
    Chan, Emily
    Lordick, Florian
    Punt, Cornelis J. A.
    Strickland, Andrew H.
    Wilson, Gregory
    Ciuleanu, Tudor-Eliade
    Roman, Laslo
    Van Cutsem, Eric
    Tzekova, Valentina
    Collins, Simon
    Oliner, Kelly S.
    Rong, Alan
    Gansert, Jennifer
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (31) : 4706 - 4713