EGFR Antibodies in Colorectal Cancer: Where Do They Belong?

被引：34

作者：

Grothey, Axel ^{[1
]}

机构：

[1] Mayo Clin, Rochester, MN 55905 USA

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2010年 / 28卷 / 31期

关键词：

PHASE-III TRIAL; 1ST-LINE TREATMENT; CETUXIMAB; PANITUMUMAB; FLUOROURACIL; BEVACIZUMAB; OXALIPLATIN; LEUCOVORIN; IRINOTECAN; CHEMOTHERAPY;

D O I：

10.1200/JCO.2010.29.3407

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：4668 / 4670

页数：4

共 18 条

[1] Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer [J].

Amado, Rafael G. ;

Wolf, Michael ;

Peeters, Marc ;

Van Cutsem, Eric ;

Siena, Salvatore ;

Freeman, Daniel J. ;

Juan, Todd ;

Sikorski, Robert ;

Suggs, Sid ;

Radinsky, Robert ;

Patterson, Scott D. ;

Chang, David D. .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (10) :1626-1634

[2]

[Anonymous], J CLIN ONCOL S

[3] Biomarkers of Resistance to Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients with Metastatic Colorectal Cancer [J].

Banck, Michaela S. ;

Grothey, Axel .

CLINICAL CANCER RESEARCH, 2009, 15 (24) :7492-7501

[4] Fluorouracil, Leucovorin, and Oxaliplatin With and Without Cetuximab in the First-Line Treatment of Metastatic Colorectal Cancer [J].

Bokemeyer, Carsten ;

Bondarenko, Igor ;

Makhson, Anatoly ;

Hartmann, Joerg T. ;

Aparicio, Jorge ;

de Braud, Filippo ;

Donea, Serban ;

Ludwig, Heinz ;

Schuch, Gunter ;

Stroh, Christopher ;

Loos, Anja H. ;

Zubel, Angela ;

Koralewski, Piotr .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (05) :663-671

[5] Randomized, Phase III Trial of Panitumumab With Infusional Fluorouracil, Leucovorin, and Oxaliplatin (FOLFOX4) Versus FOLFOX4 Alone As First-Line Treatment in Patients With Previously Untreated Metastatic Colorectal Cancer: The PRIME Study [J].

Douillard, Jean-Yves ;

Siena, Salvatore ;

Cassidy, James ;

Tabernero, Josep ;

Burkes, Ronald ;

Barugel, Mario ;

Humblet, Yves ;

Bodoky, Gyoergy ;

Cunningham, David ;

Jassem, Jacek ;

Rivera, Fernando ;

Kocakova, Ilona ;

Ruff, Paul ;

Blasinska-Morawiec, Maria ;

Smakal, Martin ;

Canon, Jean-Luc ;

Rother, Mark ;

Oliner, Kelly S. ;

Wolf, Michael ;

Gansert, Jennifer .

JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (31) :4697-4705

[6] Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial [J].

Folprecht, Gunnar ;

Gruenberger, Thomas ;

Bechstein, Wolf O. ;

Raab, Hans-Rudolf ;

Lordick, Florian ;

Hartmann, Joerg T. ;

Lang, Hauke ;

Frilling, Andrea ;

Stoehlmacher, Jan ;

Weitz, Juergen ;

Konopke, Ralf ;

Stroszczynski, Christian ;

Liersch, Torsten ;

Ockert, Detlev ;

Herrmann, Thomas ;

Goekkurt, Eray ;

Parisi, Fabio ;

Koehne, Claus-Henning .

LANCET ONCOLOGY, 2010, 11 (01) :38-47

[7] A Randomized Phase IIIB Trial of Chemotherapy, Bevacizumab, and Panitumumab Compared With Chemotherapy and Bevacizumab Alone for Metastatic Colorectal Cancer [J].

Hecht, J. Randolph ;

Mitchell, Edith ;

Chidiac, Tarek ;

Scroggin, Carroll ;

Hagenstad, Christopher ;

Spigel, David ;

Marshall, John ;

Cohn, Allen ;

McCollum, David ;

Stella, Philip ;

Deeter, Robert ;

Shahin, Seta ;

Amado, Rafael G. .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (05) :672-680

[8] K-ras mutations and benefit from cetuximab in advanced colorectal cancer [J].

Karapetis, Christos S. ;

Khambata-Ford, Shirin ;

Jonker, Derek J. ;

O'Callaghan, Chris J. ;

Tu, Dongsheng ;

Tebbutt, Niall C. ;

Simes, R. John ;

Chalchal, Haji ;

Shapiro, Jeremy D. ;

Robitaille, Sonia ;

Price, Timothy J. ;

Shepherd, Lois ;

Au, Heather-Jane ;

Langer, Christiane ;

Moore, Malcolm J. ;

Zalcberg, John R. .

NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (17) :1757-1765

[9]

MAUGHAN TS, 2010, J CLIN ONCOL S, V28, pS261

[10] Randomized Phase III Study of Panitumumab With Fluorouracil, Leucovorin, and Irinotecan (FOLFIRI) Compared With FOLFIRI Alone As Second-Line Treatment in Patients With Metastatic Colorectal Cancer [J].

Peeters, Marc ;

Price, Timothy Jay ;

Cervantes, Andres ;

Sobrero, Alberto F. ;

Ducreux, Michel ;

Hotko, Yevhen ;

Andre, Thierry ;

Chan, Emily ;

Lordick, Florian ;

Punt, Cornelis J. A. ;

Strickland, Andrew H. ;

Wilson, Gregory ;

Ciuleanu, Tudor-Eliade ;

Roman, Laslo ;

Van Cutsem, Eric ;

Tzekova, Valentina ;

Collins, Simon ;

Oliner, Kelly S. ;

Rong, Alan ;

Gansert, Jennifer .

JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (31) :4706-4713

← 1 2 →