Alkylation of ethyl pyruvate via reductive coupling of alkenes and ethyl 2-(benzenesulfonylamino)acrylate

被引：9

作者：

Darmency, V ^{[1
]}

Renaud, P ^{[1
]}

机构：

[1] Univ Bern, Dept Chem & Biochem, CH-3012 Bern, Switzerland

来源：

CHIMIA | 2005年 / 59卷 / 03期

关键词：

alkylation; enamides; hydroboration; organoboranes; radical reactions; sulfonamides;

D O I：

10.2533/000942905777676722

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Radical coupling of B-alkylcatecholboranes, in situ generated from the corresponding alkenes, with ethyl 2-(benzenesulfonylamino)acrylate is reported. This reaction represents an extension of the radical allylation of B-alkylcatecholboranes by allylsulfones. This unique process allows the preparation of various alpha-ketoesters (alkylated pyruvates) in a straightforward manner. It also demonstrates the generality of-the radical mediated C-C bond formation starting from organoboranes and allylic benzenesulfonyl derivatives.

引用

页码：109 / 110

页数：2

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