Alternaria-Associated Fungus Ball of Orbit Nose and Paranasal Sinuses: Case Report of a Rare Clinical Entity

被引:11
作者
Pesic, Zoran [1 ]
Otasevic, Suzana [2 ]
Mihailovic, Dragan [3 ]
Petrovic, Sladjana [4 ]
Arsic-Arsenijevic, Valentina [5 ]
Stojanov, Dragan [4 ]
Petrovic, Milica [6 ]
机构
[1] Univ Nis, Fac Med, Dept Maxillofacial Surg, Nish 18000, Serbia
[2] Univ Nis, Dept Microbiol & Immunol, Fac Med, Nish 18000, Serbia
[3] Univ Nis, Dept Pathol, Fac Med, Nish 18000, Serbia
[4] Univ Nis, Dept Radiol, Fac Med, Nish 18000, Serbia
[5] Univ Belgrade, Dept Microbiol & Immunol, Fac Med, Belgrade 11000, Serbia
[6] Univ Nis, Dept Prosthodont, Fac Med, Nish 18000, Serbia
关键词
Fungal ball; Paranasal sinuses; Alternaria alternata; Diagnosis; Treatment;
D O I
10.1007/s11046-015-9881-6
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Alternaria-associated fungus ball of maxillar, ethmoidal paranasal sinuses, nasal cavity and orbit with bone erosion is extremely rare. Till recently, only two cases of this infection in immune competitive patients have been reported. We are herein describing the case of immune-competent woman who suffered of nasal congestion for 10 years. Patient was treated for tumor-like lesion in right maxillar sinus, where propagation in right nose cavity, right ethmoidal cells and right orbita was present. The organism that was seen in surgical removal of fungal debris by histological study, in using mycological testing, was proven as Alternaria alternata. Combination of surgical intervention and treatment with itraconazole eradicated fungal infection, and the disease was not relapsed in follow-up period of 2 years.
引用
收藏
页码:99 / 103
页数:5
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  • [11] Perspectives on the etiology of chronic rhinosinusitis
    Tan, Bruce K.
    Schleimer, Robert P.
    Kern, Robert C.
    [J]. CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY, 2010, 18 (01) : 21 - 26
  • [12] EUCAST Technical Note on the method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for conidia-forming moulds - Subcommittee on antifungal susceptibility testing (AFST) of the ESCMID European committee for antimicrobial susceptibility testing (EUCAST)
    Tudela, J. -L. Rodriquez
    Donnelly, J. P.
    Arendrup, M. C.
    Arikan, S.
    Barchiesi, F.
    Bille, J.
    Chryssanthou, E.
    Cuenca-Estrella, M.
    Dannaoui, E.
    Denning, D.
    Fegeler, W.
    Gaustad, P.
    Lass-Florl, C.
    Moore, C.
    Richardson, M.
    Schmalreck, A.
    Velegraki, J. A.
    Verweij, P.
    [J]. CLINICAL MICROBIOLOGY AND INFECTION, 2008, 14 (10) : 982 - 984