Community strains of methicillin-resistant Staphylococcus aureus as potential cause of healthcare-associated infections, Uruguay,2002-2004

被引：42

作者：

Benoit, Stephen R. ^{[1
]}

Estivariz, Concepcion ^{[1
]}

Mogdasy, Cristina ^{[2
]}

Pedreira, Walter ^{[3
]}

Galiana, Antonio ^{[3
]}

Galiana, Alvaro ^{[4
]}

Bagnulo, Homero ^{[3
]}

Gorwitz, Rachel ^{[1
]}

Fosheim, Gregory E. ^{[1
]}

McDougal, Linda K. ^{[1
]}

Jernigan, Daniel ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA

[2] Asociac Espanola, Montevideo, Uruguay

[3] Hosp Maciel, Montevideo, Uruguay

[4] Hosp Pereira Rossell, Montevideo, Uruguay

来源：

EMERGING INFECTIOUS DISEASES | 2008年 / 14卷 / 08期

关键词：

D O I：

10.3201/eid1408.071183

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Community-associated methicillin-resistant Staphylococcus aureus(CA-MRSA) strains have emerged in Uruguay. We reviewed S. aureus isolates from a large healthcare facility in Montevideo (center A) and obtained information from 3 additional hospitals on patients infected with CA-MRSA. An infection was defined as healthcare-onset if the culture was obtained > 48 hours after hospital admission. At center A, the proportion of S. aureus infections caused by CA-MRSA increased from 4% to 23% over 2 years; the proportion caused by healthcare-associated MRSA (HA-MRSA) decreased from 25% to 5%. Of 182 patients infected with CA-MRSA, 38 (21 %) had healthcare-onset infections. Pulsed-field gel electrophoresis determined that 22 (92%) of 24 isolates were USA1100, a community strain. CA-MRSA has emerged in Uruguay and appears to have replaced HA-MRSA strains at 1 healthcare facility. In addition, CA-MRSA appears to cause healthcare-onset infections, a finding that emphasizes the need for infection control measures to prevent transmission within healthcare settings.

引用

页码：1216 / 1223

页数：8

共 40 条

[1] An outbreak of community-onset methicillin-resistant Staphylococcus aureus skin infections in southwestern Alaska [J].