Hematologic Parameters and Angiographic Progression of Coronary Atherosclerosis

被引：146
作者：
Kalay, Nihat [1 ]
Dogdu, Orhan [1 ]
Koc, Fatih [2 ]
Yarlioglues, Mikail [1 ]
Ardic, Idris [1 ]
Akpek, Mahmut [1 ]
Cicek, Davran [3 ]
Oguzhan, Abdurrahman [1 ]
Ergin, Ali [1 ]
Kaya, Mehmet G. [1 ]
机构：
[1] Erciyes Univ, Fac Med, Dept Cardiol, TR-38000 Kayseri, Turkey
[2] Gaziosmanpasa Univ, Dept Cardiol, Tokat, Turkey
[3] Baskent Univ, Sch Med, Dept Cardiol, Antalya, Turkey
来源：
ANGIOLOGY | 2012年 / 63卷 / 03期
关键词：
hematologic parameters; neutrophil/lymphocyte ratio; progression; atherosclerosis; DENSITY-LIPOPROTEIN CHOLESTEROL; LIFE-STYLE MODIFICATION; PLAQUE PROGRESSION; ARTERY-DISEASE; MORTALITY; RISK;
D O I：
10.1177/0003319711412763
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
Hematologic parameters have prognostic importance in cardiovascular disease. However, the relation between atherosclerosis progression and hematologic parameters is not well defined. A total of 394 patients requiring repeat coronary angiography were included in the study. According to angiography, patients were divided into 2 groups, progressive (n = 196) and nonprogressive (n = 198) diseases. Hematologic parameters including mean platelet volume (MPV) and neutrophil/lymphocyte (N/L) ratio were measured. Glucose, creatinine, and cholesterol were significantly higher in the progressive group. Mean platelet volume count was similar in both groups. The N/L ratio was significantly higher in the progressive group (5.0 +/- 5.1 vs 3.2 +/- 3; P = .001). In multivariate analysis, the N/L ratio was significantly related with progression (relative risk [RR]: 2.267, 95% CI: 1.068-4.815, P = .03). Progression rate was significantly high in patients with high N/L ratio (39% vs 56%). Our results suggest that the N/L ratio is a predictor of progression of atherosclerosis.
引用
收藏
页码：213 / 217
页数：5
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