Selective Tandem Synthesis of Oximes from Benzylic Alcohols Catalyzed with 2, 3-Dichloro-5, 6-dicyanobenzoquinone

被引：5

作者：

Aghapour, Ghasem ^{[1
]}

Mohamadian, Samaneh ^{[1
]}

机构：

[1] Damghan Univ, Sch Chem, Damghan 36715364, Iran

来源：

BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2012年 / 33卷 / 04期

关键词：

Alcohol; Oxime; 2,3-Dichloro-5,6-dicyanobenzoquinone; Tandem synthesis; FACILE CONVERSION; PRIMARY AMIDES; EFFICIENT; ALDEHYDES; ALKYLATION; ALDOXIMES; NITRILES; BENZALDOXIMES; FORMYLATION; INHIBITORS;

D O I：

10.5012/bkcs.2012.33.4.1209

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In spite of many reports in the literature concerning with oxidation of benzylic alcohols to carbonyl compounds with 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) in stoichiometric amounts or even more, we surprisingly found that benzylic alcohols are directly oxidized to oximes using a catalytic amount of DDQ in the presence of hydroxylamine hydrochloride under solvent-free conditions. The present tandem catalytic method can be efficiently used for preparation of oximes in the presence of some other functional groups with excellent chemoselectivity.

引用

页码：1209 / 1212

页数：4