Herba Artemisiae annuae tea preparation compared to sulfadoxine-pyrimethamine in the treatment of uncomplicated falciparum malaria in adults:: a randomized double-blind clinical trial

被引：25

作者：

Blanke, Christoph H. ^{[1
]}

Naisabha, Godson B. ^{[1
]}

Balema, Mussa B. ^{[1
]}

Mbaruku, Godfrey M. ^{[2
]}

Heide, Lutz ^{[3
]}

Mueller, Markus S. ^{[4
]}

机构：

[1] Diocese Western Tanganyika, Matyazo Hlth Ctr, Kigoma, Tanzania

[2] Reg Med Off, Kigoma, Tanzania

[3] Univ Tubingen, Inst Pharmaceut, Dept Pharmaceut Biol, D-72076 Tubingen, Germany

[4] German Inst Med Mission, D-72076 Tubingen, Germany

来源：

TROPICAL DOCTOR | 2008年 / 38卷 / 02期

关键词：

D O I：

10.1258/td.2007.060184

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Tea preparations from the herb Artemisia annua L. (Aa) which is used in traditional Chinese medicine might offer an inexpensive way of producing artemisinin drugs locally. We compared Aa with sulfadoxine-pyrimethamine (SP) in the treatment of uncomplicated falciparum malaria in semi-immune adults. After seven days, the cure rate was 7/10 for the Aa compared to 7/9 for SP; this dropped to 4/10 for Aa and 4/9 for SP at day 14 and to 1/9 for Aa and 3/8 for SP at day 28.

引用

页码：113 / 116

页数：4

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