Attitudes of patients with spondylarthritis or rheumatoid arthritis regarding biological treatment during COVID-19 pandemic: A multi-center, phone-based, cross-sectional study

被引:4
|
作者
Zateri, Coskun [1 ]
Birtane, Murat [2 ]
Aktas, Ilknur [3 ]
Sarikaya, Selda [4 ]
Rezvani, Aylin [5 ]
Altan, Lale [6 ]
Dursun, Nigar [7 ]
Dursun, Erbil [7 ]
Tastekin, Nurettin [2 ]
Celiker, Reyhan [8 ]
Ozdolap, Senay [4 ]
Akgun, Kenan [9 ]
机构
[1] Canakkale Onsekiz Mart Univ, Fac Med, Dept Phys Med & Rehabil, TR-17020 Canakkale, Turkey
[2] Trakya Univ, Fac Med, Dept Phys Med & Rehabil, Edirne, Turkey
[3] Hlth Sci Univ, Fatih Sultan Mehmet Training & Res Hosp, Dept Phys Med & Rehabil, Istanbul, Turkey
[4] Bulent Ecevit Univ, Fac Med, Dept Phys Med & Rehabil, Zonguldak, Turkey
[5] Medipol Univ, Int Fac Med, Dept Phys Med & Rehabil, Istanbul, Turkey
[6] Uludag Univ, Fac Med, Dept Phys Med & Rehabil, Bursa, Turkey
[7] Kocaeli Univ, Fac Med, Dept Phys Med & Rehabil, Kocaeli, Turkey
[8] Acibadem Univ, Fac Med, Dept Phys Med & Rehabil, Istanbul, Turkey
[9] Istanbul Univ, Cerrahpasa Fac Med, Dept Phys Med & Rehabil, Istanbul, Turkey
关键词
Biological therapy; COVID-19; pandemic; rheumatoid arthritis; spondylarthritis;
D O I
10.46497/ArchRheumatol.2021.8364
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: In this study, we aimed to investigate the medical treatment attitudes of patients with spondylarthritis or rheumatoid arthritis (RA) who were using biological drugs during the novel coronavirus-2019 (COVID-19) pandemic. Patients and methods: In this multi-center, cross-sectional study, a total of 277 patients (178 males, 99 females; median age: 45 years; range, 20 to 77 years) who were using biological disease-modifying anti-rheumatic drugs (bDMARDs) for rheumatic diseases and were reached by phone between June 1st, 2020 and June 30th, 2020 were included. Demographic characteristics, working status, type of the rheumatic disease, comorbidities, smoking habits, and type of the bDMARDs were recorded. Disease activity was evaluated using the Visual Analog Scale (VAS). The patients were asked whether they continued the treatment plan, as it was before or changed and, if changed, how they changed the plan and what happened after the change. Results: Of the patients, 229 had spondylarthritis and 48 had RA. A total of 36.1% of the patients were smokers, and the most common comorbidity was hypertension (17.3%). Totally, 5.8% of the patients had a history of contact with a COVID-19 positive person. Only three (1.1%) patients were diagnosed with COVID-19 infection and none of them died. Of the patients, 64.3% continued their treatment, while 35.7% adopted various changes. Most patients made the decision about the treatment plan on their own (n=160, 57.8%), while 38.3% of them consulted their physicians and 13.9% of them consulted any health staff. The only significant parameter for changing the drug course was receiving intravenous bDMARDs (by infusion at hospital) (p=0.001). These patients had also a higher disease activity as measured by VAS, compared to the patients receiving non-infusion therapy (p=0.021). As a result of these changes, severity of the symptoms increased in 91 (32.9%) patients. Disruption of regular biological treatment and prior infusion therapy more likely worsened the complaints (p<0.001 and p=0.024, respectively). Conclusion: Intravenous bDMARD therapy seems to be the main factor affecting the continuity of the treatment in the pandemic period. During the pandemic period, alternative treatment options should be considered other than infusion therapy not to interrupt the treatment of these patients.
引用
收藏
页码:473 / 481
页数:9
相关论文
共 50 条
  • [1] Effects of COVID-19 pandemic on medical students in Jordanian universities: A multi-center cross-sectional study
    AL-Husban, Naser
    Alkhayat, Aysha
    Aljweesri, Mariam
    Alharbi, Reem
    Aljazzaf, Zahraa
    Al-Husban, Nehad
    Elmuhtaseb, Mohammed S.
    Al Oweidat, Khaled
    Obeidat, Nail
    ANNALS OF MEDICINE AND SURGERY, 2021, 67
  • [2] Predictors of anxiety and depression in operating room nurses during the COVID-19 pandemic: A multi-center cross-sectional study
    Aktas, Filiz Ogce
    Damar, Hale Turhan
    Ozkul, Burcu
    Voight, Patrick
    Fisher, Mona Guckian
    Elin, Michael
    Sharma, Suresh K.
    Bird, Sarah
    WORK-A JOURNAL OF PREVENTION ASSESSMENT & REHABILITATION, 2024, 78 (02): : 279 - 293
  • [3] Changes in treatment adherence and behaviour during the COVID-19 pandemic in Japanese patients with rheumatoid arthritis: Results from cross-sectional study in the IORRA cohort
    Tanaka, Eiichi
    Inoue, Eisuke
    Abe, Mai
    Saka, Kumiko
    Sugano, Eri
    Ochiai, Moeko
    Yamaguchi, Rei
    Ikari, Katsunori
    Yamanaka, Hisashi
    Harigai, Masayoshi
    MODERN RHEUMATOLOGY, 2022, 32 (06) : 1193 - 1195
  • [4] Assessment of Positive Airway Pressure Treatment Adherence and Sleep Quality in Sleep Apnea Patients during COVID-19 Pandemic: Multi-center Cross-sectional Study Results
    Ozdilekcan, Cigdem
    Firat, Hikmet
    Demir, Ahmet Ugur
    Yuceege, Melike
    Akcay, Bulent Devrim
    IRANIAN RED CRESCENT MEDICAL JOURNAL, 2023, 25 (03)
  • [5] Perceptions and behaviours related to COVID-19 in patients with rheumatoid arthritis: a cross-sectional study
    Takahiro Itaya
    Mie Torii
    Motomu Hashimoto
    Kazuaki Jindai
    Wataru Yamamoto
    Kyosuke Tanigawa
    Yuki Urai
    Ayae Kinoshita
    Kazuko Nin
    Ryu Watanabe
    Koichi Murata
    Kosaku Murakami
    Masao Tanaka
    Hiromu Ito
    Shuichi Matsuda
    Akio Morinobu
    Clinical Rheumatology, 2022, 41 : 45 - 51
  • [6] Perceptions and behaviours related to COVID-19 in patients with rheumatoid arthritis: a cross-sectional study
    Itaya, Takahiro
    Torii, Mie
    Hashimoto, Motomu
    Jindai, Kazuaki
    Yamamoto, Wataru
    Tanigawa, Kyosuke
    Urai, Yuki
    Kinoshita, Ayae
    Nin, Kazuko
    Watanabe, Ryu
    Murata, Koichi
    Murakami, Kosaku
    Tanaka, Masao
    Ito, Hiromu
    Matsuda, Shuichi
    Morinobu, Akio
    CLINICAL RHEUMATOLOGY, 2022, 41 (01) : 45 - 51
  • [7] Psychosocial and clinical impact of COVID-19 pandemic and its relationship to the quality of life in patients with rheumatoid arthritis: a cross-sectional study, Egypt
    Hassan, Mervat S.
    Mostafa, Dalia, I
    Abdelhady, Enas, I
    Sarhan, Shymaa A.
    Abdelghani, Mohamed
    Seleem, Dina A.
    MIDDLE EAST CURRENT PSYCHIATRY-MECPSYCH, 2022, 29 (01):
  • [8] Dental Students' Attitudes and Perspectives regarding Online Learning during the COVID-19 Pandemic: a Cross-sectional, Multi-university Study
    Vrazic, Domagoj
    Music, Larisa
    Barbaric, Marina
    Badovinac, Ana
    Plancak, Laura
    Puhar, Ivan
    ACTA STOMATOLOGICA CROATICA, 2022, 56 (04) : 395 - 404
  • [9] Physicians' Attitudes Toward Telemedicine Consultations During the COVID-19 Pandemic: Cross-sectional Study
    Alhajri, Noora
    Simsekler, Mecit Can Emre
    Alfalasi, Buthaina
    Alhashmi, Mohamed
    AlGhatrif, Majd
    Balalaa, Nahed
    Al Ali, Maryam
    Almaashari, Raghda
    Al Memari, Shammah
    Al Hosani, Farida
    Al Zaabi, Yousif
    Almazroui, Shereena
    Alhashemi, Hamed
    Baltatu, Ovidiu C.
    JMIR MEDICAL INFORMATICS, 2021, 9 (06)
  • [10] Investigation of recurrence of joint symptoms after COVID-19 in patients with rheumatoid arthritis: Cross-sectional study
    Akbarpour, Afsaneh
    Salesi, Mansour
    Babak, Anahita
    JOURNAL OF RESEARCH IN MEDICAL SCIENCES, 2024, 29 (01):