A New Direction in C-H Alkenylation: Silanol as a Helping Hand

被引：75

作者：

Mewald, Marius ^{[1
]}

Schiffner, Julia A. ^{[1
]}

Oestreich, Martin ^{[1
]}

机构：

[1] Tech Univ Berlin, Inst Chem, D-10623 Berlin, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 08期

关键词：

alkenylation; C?H activation; cross-coupling; directing groups; silicon; ORTHO-HALOGENATION; OLEFINATION; FUNCTIONALIZATION; ACYLOXYLATION; ACTIVATION; PYDIPSI;

D O I：

10.1002/anie.201107859

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Director's cut: Not only conventional alcohols but also silanols can act as directing groups in oxidative palladium(II)-catalyzed C-H alkenylations. The silicon-tethered hydroxy groups are traceless, thereby facilitating the regioselective C-H activation of toluene derivitives as well as phenols (see scheme). © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1763 / 1765

页数：3

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