In vivo evaluation of plasma sprayed hydroxyapatite coatings having different crystallinity

被引：144

作者：

Xue, WC ^{[1
]}

Tao, SY ^{[1
]}

Liu, XY ^{[1
]}

Zheng, XB ^{[1
]}

Ding, CX ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Ceram, Shanghai 200050, Peoples R China

来源：

BIOMATERIALS | 2004年 / 25卷 / 03期

基金：

中国国家自然科学基金;

关键词：

vapor-flame treatment; hydroxyapatite coating; crystallinity; dissolution; in vivo;

D O I：

10.1016/S0142-9612(03)00545-3

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

In this paper, hydroxyapatite (HA) coatings having the crystallinities of 56% and 98% were deposited by the plasma spraying and vapor-flame treatment process. The phase composition and crystallinity of the coatings were investigated by X-ray diffraction and infrared spectra, The dissolution behavior of the coatings in tris-buffer solutions was examined. The results obtained indicated that the coating having the high crystallinity showed the lower dissolution as compared to the low crystallinity coating. The bone bonding ability of HA coatings were observed in vivo by implanted in dog's femur. After 3 months implantation, the high crystallinity coating showed the higher shear strengths and remained integrated, whereas the separation of the coating fragments was clearly observed in the coating having low crystallinity. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：415 / 421

页数：7

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