Catalytic Asymmetric Cross-Dehydrogenative Coupling of 2H-Chromenes and Aldehydes

被引：21

作者：

Pan, Xinhui ^{[1
,3
]}

Liu, Xigong ^{[1
]}

Sun, Shutao ^{[1
]}

Meng, Zhilin ^{[1
]}

Liu, Lei ^{[1
,2
]}

机构：

[1] Shandong Univ, Sch Pharmaceut Sci, Jinan 250012, Shandong, Peoples R China

[2] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Shandong, Peoples R China

[3] Shihezi Univ, Minist Educ, Sch Pharmaceut Sci, Key Lab Xinjiang Phytomed Resource & Utilizat, Shihezi 832002, Xinjiang, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2018年 / 36卷 / 12期

基金：

中国国家自然科学基金;

关键词：

asymmetric catalysis; C-H functionalization; 2H-chromene; aldehyde; oxidation; synthetic method; C-H BONDS; TERTIARY-AMINES; OXOCARBENIUM IONS; TETRAHYDROISOQUINOLINE DERIVATIVES; MOLECULAR-OXYGEN; TERMINAL ALKYNES; NITROGEN ATOM; FUNCTIONALIZATION; ALKYNYLATION; PHOTOREDOX;

D O I：

10.1002/cjoc.201800369

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first catalytic asymmetric cross-dehydrogenative coupling of 2H-chromenes with aldehydes using o-chloranil (3,4,5,6-tetrachloro-1,2- benzoquinone) as an oxidant has been described. The organocatalytic process is tolerated with a broad range of structurally and electronically varied 2H-chromenes and aldehydes with good yield and high enantiocontrol.

引用

页码：1187 / 1190

页数：4

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