Two diketopiperazines and one halogenated phenol from cultures of the marine bacterium, Pseudoalteromonas luteoviolacea

被引：39
作者：
Jiang, Z
Boyd, KG
Mearns-Spragg, A
Adams, DR
Wright, PC
Burgess, JG
机构：
[1] Heriot Watt Univ, Dept Biol Sci, Edinburgh EH14 4AS, Midlothian, Scotland
[2] Heriot Watt Univ, Dept Chem, Edinburgh EH14 4AS, Midlothian, Scotland
[3] Heriot Watt Univ, Dept Mech & Chem Engn, Edinburgh EH14 4AS, Midlothian, Scotland
来源：
NATURAL PRODUCT LETTERS | 2000年 / 14卷 / 06期
关键词：
cyclo-(L-prolyl-L-glycine); cyclo-(L-phenylalanyl-4R-hydroxy-L-proline); 2,4-dibromo-6-chlorophenol; Pseudoalteromonas luteoviolacea; antibiotic;
D O I：
10.1080/10575630008043781
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two diketopiperazines, cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline), and 2,4-dibromo-6-chlorophenol were isolated from cultures of the marine bacterium, Pseudoalteromonas luteoviolacea. Cyclo-(L-prolyl-L-glycine) and cyclo-(L-phenylalanyl-4R-hydroxy-L-proline) stimulated antibiotic production in this strain. 2,4-Dibromo-6-chlorophenol showed antibacterial activity against methicillin resistant Staphylococcus aureus (MRSA) and the cystic fibrosis associated pathogen Burkholderia cepacia.
引用
收藏
页码：435 / 440
页数：6
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