Leucine-Rich Glioma Inactivated-1 and Voltage-Gated potassium Channel Autoimmune Encephalitis Associated with Ischemic Stroke: A Case Report

被引:2
作者
McGinley, Marisa [1 ]
Morales-Vidal, Sarkis [2 ]
Ruland, Sean [1 ]
机构
[1] Loyola Univ, Med Ctr, Dept Neurol, 2160 S 1st Ave, Maywood, IL 60153 USA
[2] Florida Hosp Tampa, Dept Neurol, Tampa, FL USA
关键词
leucine-rich glioma inactivated-1; voltage-gated potassium channel; autoimmune encephalitis; limbic encephalitis; ischemic stroke; LIMBIC ENCEPHALITIS; ANTIBODIES; COMPLEX;
D O I
10.3389/fneur.2016.00068
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Autoimmune encephalitis is associated with a wide variety of antibodies and clinical presentations. Voltage-gated potassium channel (VGKC) antibodies are a cause of autoimmune non-paraneoplastic encephalitis characterized by memory impairment, psychiatric symptoms, and seizures. We present a case of VGKC encephalitis likely preceding an ischemic stroke. Reports of autoimmune encephalitis associated with ischemic stroke are rare. Several hypotheses linking these two disease processes are proposed.
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