Palladium-catalyzed carbonylative cyclization of β-bromo-α,β-unsaturated carboxylic acids with primary amines leading to N-alkylmaleimides

被引：15
作者：
Lee, Hye Kyung [1 ]
Cho, Chan Sik [1 ]
机构：
[1] Kyungpook Natl Univ, Dept Appl Chem, Taegu 702701, South Korea
来源：
APPLIED ORGANOMETALLIC CHEMISTRY | 2012年 / 26卷 / 04期
基金：
新加坡国家研究基金会;
关键词：
ss-bromo-a; ss-unsaturated carboxylic acids; carbonylative cyclization; palladium catalyst; primary amines; N-alkylmaleimides; BETA-BROMOVINYL ALDEHYDES; SUBSTITUTED BENZENE-DERIVATIVES; GENERAL-METHOD; OXIDATIVE CYCLIZATION; HECK CYCLIZATION; HALO-ENONES; QUINOLINES; ALKYLIDENEFURANONES; CYCLOPENTENONES; AROMATIZATION;
D O I：
10.1002/aoc.2836
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Cyclic beta-bromo-a,beta-unsaturated carboxylic acids are carbonylatively cyclized with primary amines under carbon monoxide pressure in MeCN in the presence of a catalytic amount of PdCl2(PPh3)2 to give N-alkylmaleimides. Copyright (C) 2012 John Wiley & Sons, Ltd.
引用
收藏
页码：185 / 188
页数：4
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