A self-assembled nanopatch with peptide-organic multilayers and mechanical properties

被引：13

作者：

Liu, Lei ^{[1
,2
,3
]}

Li, Yibao ^{[4
,5
]}

Xia, Dan ^{[1
,2
]}

Bortolini, Christian ^{[1
,2
]}

Zhang, Shuai ^{[1
,2
]}

Yang, Yanlian ^{[5
]}

Pedersen, Jan S. ^{[1
,2
]}

Wang, Chen ^{[5
]}

Besenbacher, Flemming ^{[1
,2
]}

Dong, Mingdong ^{[1
,2
]}

机构：

[1] Aarhus Univ, Interdisciplinary Nanosci Ctr iNANO, Ctr DNA Nanotechnol CDNA, DK-8000 Aarhus C, Denmark

[2] Aarhus Univ, Dept Phys & Astron, DK-8000 Aarhus C, Denmark

[3] Jiangsu Univ, Inst Adv Mat, Zhenjiang, Jiangsu, Peoples R China

[4] Gannan Normal Univ, Key Lab Organopharmaceut Chem, Ganzhou 341000, Peoples R China

[5] Natl Ctr Nanosci & Technol, Beijing, Peoples R China

来源：

NANOSCALE | 2015年 / 7卷 / 06期

基金：

新加坡国家研究基金会; 中国国家自然科学基金;

关键词：

POLYPEPTIDES; NANOTUBES;

D O I：

10.1039/c4nr03797a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Peptides enable the construction of a diversity of one-dimensional (1D) and zero-dimensional (0D) nanostructures by molecular self-assembly. To date, it is a great challenge to construct two-dimensional (2D) nanostructures from peptides. Here we introduce an organic molecule to tune the amphiphilic-like peptide assembly to form a peptide-organic 2D nanopatch structure. The nanomechanical properties of the nanopatch were explored by quantitative nanomechanical imaging and force control manipulation. The peptide-organic patches are multilayers composed of several domains, which can be peeled off stepwise. The patch formation provides an approach towards constructing 2D nanostructures by peptide-organic assembly and it could be potentially utilized in a wide range of applications such as functional biomaterials.

引用

页码：2250 / 2254

页数：5

共 30 条

[1] Measurement of intrinsic properties of amyloid fibrils by the peak force QNM method [J].