Pregnancy and autoimmune connective tissue diseases

被引：57

作者：

Marder, Wendy ^{[1
,2
]}

Littlejohn, Emily A. ^{[1
]}

Somers, Emily C. ^{[1
,2
,3
,4
,5
,6
]}

机构：

[1] Univ Michigan, Sch Med, Dept Internal Med, NCRC B14-G236,2800 Plymouth Rd,NCRC B300-304M, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Sch Med, Dept OB GYN, NCRC B14-G236,2800 Plymouth Rd, Ann Arbor, MI 48109 USA

[3] Univ Michigan, Sch Med, Dept Environm Hlth Sci, NCRC B14-G236,2800 Plymouth Rd, Ann Arbor, MI 48109 USA

[4] Univ Michigan, Sch Publ Hlth, Dept Internal Med, NCRC B14-G236,2800 Plymouth Rd, Ann Arbor, MI 48109 USA

[5] Univ Michigan, Sch Publ Hlth, Dept OB GYN, NCRC B14-G236,2800 Plymouth Rd, Ann Arbor, MI 48109 USA

[6] Univ Michigan, Sch Publ Hlth, Dept Environm Hlth Sci, NCRC B14-G236,2800 Plymouth Rd, Ann Arbor, MI 48109 USA

来源：

BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY | 2016年 / 30卷 / 01期

关键词：

Antiphospholipid antibody syndrome; Autoimmunity; Myositis; Pregnancy; Rheumatoid arthritis; Scleroderma; Sjogren's syndrome; Systemic lupus erythematosus; SYSTEMIC-LUPUS-ERYTHEMATOSUS; CONGENITAL HEART-BLOCK; DEFINITE ANTIPHOSPHOLIPID SYNDROME; INTERNATIONAL CONSENSUS STATEMENT; NECROSIS-FACTOR ANTAGONISTS; INFLAMMATORY-BOWEL-DISEASE; REPRODUCTIVE RISK-FACTORS; RHEUMATOID-ARTHRITIS; DRUG-USE; CYCLOPHOSPHAMIDE THERAPY;

D O I：

10.1016/j.berh.2016.05.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Autoimmune connective tissue diseases predominantly affect women and often occur during the reproductive years. Thus, specialized issues in pregnancy planning and management are commonly encountered in this patient population. This chapter provides a current overview of pregnancy as a risk factor for onset of autoimmune disease, considerations related to the course of pregnancy in several autoimmune connective tissue diseases, and disease management and medication issues before pregnancy, during pregnancy, and in the postpartum period. A major theme that has emerged across these inflammatory diseases is that active maternal disease during pregnancy is associated with adverse pregnancy outcomes, and that maternal and fetal health can be optimized when conception is planned during times of inactive disease and through maintaining treatment regimens compatible with pregnancy. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：63 / 80

页数：18

共 145 条

[1] Successful management of systemic lupus erythematosus nephritis flare-up during pregnancy with tacrolimus [J].