Solubility study of ketoconazole in propylene glycol and ethanol mixtures at different temperatures: A laser monitoring method

被引：6
|
作者：
Jouyban-Gharamaleki, Vahid [1 ,2 ,3 ]
Jouyban, Abolghasem [1 ,2 ,4 ]
Zhao, Hongkun [5 ]
Martinez, Fleming [6 ]
Rahimpour, Elaheh [1 ,2 ,7 ]
机构：
[1] Tabriz Univ Med Sci, Pharmaceut Anal Res Ctr, Tabriz, Iran
[2] Tabriz Univ Med Sci, Fac Pharm, Tabriz, Iran
[3] Tabriz Univ Med Sci, Kimia Idea Pardaz Azarbayjan ICIPA Sci Based Co, Tabriz, Iran
[4] Tabriz Univ Med Sci, Immunol Res Ctr, Tabriz, Iran
[5] YangZhou Univ, Coll Chem & Chem Engn, Yangzhou 225002, Jiangsu, Peoples R China
[6] Univ Nacl Colombia, Fac Ciencias, Dept Farm, Grp Invest Farmaceut Fisicoquim,Sede Bogota, Cra 30 45-03, Bogota, DC, Colombia
[7] Tabriz Univ Med Sci, Food & Drug Safety Res Ctr, Tabriz, Iran
来源：
JOURNAL OF MOLECULAR LIQUIDS | 2021年 / 337卷
关键词：
Solubility; Ketoconazole; Cosolvency models; Dissolution thermodynamics; SOLID DISPERSIONS; WATER; MODEL; PHARMACOKINETICS; SOLVENTS;
D O I：
10.1016/j.molliq.2021.116060
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The solubility of ketoconazole in the mixtures of propylene glycol and ethanol is measured by a laser monitoring technique in the temperature range of 293.2-313.2 K. The generated solubility data are fitted to some linear and non-linear cosolvency models and the accuracy of each model is investigated by calculating the mean relative deviations (MRD%) for the back-calculated data. The apparent thermodynamic parameters of ketoconazole dissolution are also computed according to the van't Hoff and Gibbs equations. (C) 2021 Elsevier B.V. All rights reserved.
引用
收藏
页数：6
相关论文
共 50 条
  • [41] Testing the prediction capability of trained models: sildenafil citrate solubility in propylene glycol and 1-propanol mixtures at different temperatures
    Jouyban, Abolghasem
    Martinez, Fleming
    Rezaei, Homa
    PHYSICS AND CHEMISTRY OF LIQUIDS, 2024,
  • [42] Solubility of meloxicam in ethylene glycol-water and propylene glycol-ethanol mixtures: Experimental determination and thermodynamic analysis
    Castro, G. T.
    Loyola, J. M.
    Gasull, E. I.
    Almandoz, M. C.
    JOURNAL OF MOLECULAR LIQUIDS, 2022, 354
  • [43] Solubility and thermodynamic study of mesalazine in propylene glycol+2-propanol mixtures
    Poturcu, Kader
    Zarghampour, Aynaz
    Rahimpour, Elaheh
    Hemmati, Salar
    Zhao, Hongkun
    Jouyban, Abolghasem
    BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING, 2023, 40 (04) : 1227 - 1238
  • [44] Thermodynamic study of the solubility of acetaminophen in propylene glycol plus water cosolvent mixtures
    Jiménez, JA
    Martínez, F
    JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2006, 17 (01) : 125 - 134
  • [45] Solubility and thermodynamic study of mesalazine in propylene glycol + 2-propanol mixtures
    Kader Poturcu
    Aynaz Zarghampour
    Elaheh Rahimpour
    Salar Hemmati
    Hongkun Zhao
    Abolghasem Jouyban
    Brazilian Journal of Chemical Engineering, 2023, 40 : 1227 - 1238
  • [46] Solubility of sildenafil citrate in the binary mixtures of ethylene glycol and water at different temperatures
    Hatefi, Ayda
    Rahimpour, Elaheh
    Ghafourian, Taravat
    Martinez, Fleming
    Barzegar-Jalali, Mohammad
    Jouyban, Abolghasem
    JOURNAL OF MOLECULAR LIQUIDS, 2020, 299
  • [47] Solubility of mesalazine in polyethylene glycol 400+water mixtures at different temperatures
    Moradi, Milad
    Rahimpour, Elaheh
    Hemmati, Salar
    Martinez, Fleming
    Barzegar-Jalali, Mohammad
    Jouyban, Abolghasem
    JOURNAL OF MOLECULAR LIQUIDS, 2020, 314
  • [48] Experimental study and thermodynamic modeling of xylitol and sorbitol solubility in mixtures of methanol and ethanol at different temperatures
    Galvao, Alessandro Cazonatto
    Robazza, Weber da Silva
    Arce, Pedro Felipe
    Mocelin, Adriane
    Paludo, Ananda Regina
    JOURNAL OF MOLECULAR LIQUIDS, 2017, 248 : 509 - 514
  • [49] Solubility, Preferential Solvation, and Solvent Effect of Micoflavin in Aqueous Mixtures of Dimethylsulfoxide, Isopropanol, Propylene Glycol, and Ethanol
    Li, Xinbao
    Zhu, Yanqing
    Zhang, Xiaotian
    Farajtabar, Ali
    Hongkun, Zhao
    JOURNAL OF CHEMICAL AND ENGINEERING DATA, 2020, 65 (04): : 1976 - 1985
  • [50] Solubility of Nifedipine in Ethanol plus Water and Propylene Glycol plus Water Mixtures at 293.2 to 313.2 K
    Sardari, Faroukh
    Jouyban, Abolghasem
    INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2013, 52 (40) : 14353 - 14358
12345