Pumping based on transverse electrokinetic effects

被引:34
作者
Gitlin, I [1 ]
Stroock, AD
Whitesides, GM
Ajdari, A
机构
[1] Harvard Univ, Dept Chem & Biol Chem, Cambridge, MA 02138 USA
[2] Ecole Super Phys & Chim Ind Ville Paris, Paris, France
关键词
D O I
10.1063/1.1602560
中图分类号
O59 [应用物理学];
学科分类号
摘要
This work presents a strategy for microfluidic pumping based on transverse electro-osmotic flow in a channel with topographical features on one wall. In this channel, flow along the long axis is generated by an electric field applied across the channel. The pump operates at low (5-10 V) voltage and achieves pumping speeds up to similar to100 mum/s in submillimeter channels. The pump is straightforward to fabricate, contains no moving parts, and provides local control of the direction and strength of pumping. The performance of the pump scales favorably with decreasing size of a microchannel. (C) 2003 American Institute of Physics.
引用
收藏
页码:1486 / 1488
页数:3
相关论文
共 21 条
[1]   Transverse electrokinetic and microfluidic effects in micropatterned channels: Lubrication analysis for slab geometries [J].
Ajdari, A .
PHYSICAL REVIEW E, 2002, 65 (01) :1-016301
[2]   Microfabricated structures for integrated DNA analysis [J].
Burns, MA ;
Mastrangelo, CH ;
Sammarco, TS ;
Man, FP ;
Webster, JR ;
Johnson, BN ;
Foerster, B ;
Jones, D ;
Fields, Y ;
Kaiser, AR ;
Burke, DT .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (11) :5556-5561
[3]   A microfabricated device for sizing and sorting DNA molecules [J].
Chou, HP ;
Spence, C ;
Scherer, A ;
Quake, S .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (01) :11-13
[4]   Rapid prototyping of microfluidic systems in poly(dimethylsiloxane) [J].
Duffy, DC ;
McDonald, JC ;
Schueller, OJA ;
Whitesides, GM .
ANALYTICAL CHEMISTRY, 1998, 70 (23) :4974-4984
[5]   A microfabricated fluorescence-activated cell sorter [J].
Fu, AY ;
Spence, C ;
Scherer, A ;
Arnold, FH ;
Quake, SR .
NATURE BIOTECHNOLOGY, 1999, 17 (11) :1109-1111
[6]   Rapid microfluidic mixing [J].
Johnson, TJ ;
Ross, D ;
Locascio, LE .
ANALYTICAL CHEMISTRY, 2002, 74 (01) :45-51
[7]   SHEAR DISPERSION AND ANOMALOUS DIFFUSION BY CHAOTIC ADVECTION [J].
JONES, SW ;
YOUNG, WR .
JOURNAL OF FLUID MECHANICS, 1994, 280 :149-172
[8]   An AC magnetohydrodynamic micropump [J].
Lemoff, AV ;
Lee, AP .
SENSORS AND ACTUATORS B-CHEMICAL, 2000, 63 (03) :178-185
[9]   Transport, manipulation, and reaction of biological cells on-chip using electrokinetic effects [J].
Li, PCH ;
Harrison, DJ .
ANALYTICAL CHEMISTRY, 1997, 69 (08) :1564-1568
[10]   Surface biopassivation of replicated poly(dimethylsiloxane) microfluidic channels and application to heterogeneous immunoreaction with on-chip fluorescence detection [J].
Linder, V ;
Verpoorte, E ;
Thormann, W ;
de Rooij, NF ;
Sigrist, M .
ANALYTICAL CHEMISTRY, 2001, 73 (17) :4181-4189