A facile synthesis of chromeno[3,4-c]spiropyrrolidine-oxindoles via 1,3-dipolar cycloadditions

被引：55

作者：

Ghandi, Mehdi ^{[1
]}

Taheri, Abuzar ^{[1
]}

Abbasi, Alireza ^{[1
]}

机构：

[1] Univ Tehran, Coll Sci, Sch Chem, Tehran, Iran

来源：

TETRAHEDRON | 2010年 / 66卷 / 34期

关键词：

Azomethine ylide; 1,3-Dipolar cycloaddition; Chromeno[3,4-c]spiropyrrolidine-oxindole; AZOMETHINE YLIDES; INTRAMOLECULAR CYCLOADDITION; CONSTRUCTION; DERIVATIVES;

D O I：

10.1016/j.tet.2010.06.078

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile one-pot synthesis of chromene bearing novel spiropyrrolidine-oxindoles has been accomplished by the [3+2]-cycloaddition reaction of 3-acetyl-2H-chromen-2-ones with azomethine ylides derived in situ from isatin or N-methyl isatin with sarcosine. (C) 2010 Elsevier Ltd. All rights reserved.

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页码：6744 / 6748

页数：5

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