A self-assembling amphiphilic dendrimer nanotracer for SPECT imaging

被引：21

作者：

Ding, Ling ^{[1
,2
]}

Lyu, Zhenbin ^{[1
]}

Tintaru, Aura ^{[3
]}

Laurini, Erik ^{[4
]}

Marson, Domenico ^{[4
]}

Louis, Beatrice ^{[5
,6
]}

Bouhlel, Ahlem ^{[5
,6
]}

Balasse, Laure ^{[5
,6
]}

Fernandez, Samantha ^{[5
,6
]}

Garrigue, Philippe ^{[5
,6
]}

Mas, Eric ^{[7
]}

Giorgio, Suzanne ^{[1
]}

Pricl, Sabrina ^{[2
,8
]}

Guillet, Benjamin ^{[5
,6
]}

Peng, Ling ^{[1
]}

机构：

[1] Aix Marseille Univ, CNRS, Ctr Interdisciplinaire Nanosci Marseille, UMR 7325,Equipe Labellisee Ligue Canc, Marseille, France

[2] Aix Marseille Univ, CRMBM, CNRS, Marseille, France

[3] Aix Marseille Univ, Inst Chim Radicalaire, CNRS, UMR7273, Marseille, France

[4] Univ Trieste, DEA, Mol Biol & Nanotechnol Lab MolBNL UniTS, Trieste, Italy

[5] Aix Marseille Univ, C2VN, INRA, INSERM, Marseille, France

[6] Aix Marseille Univ, CNRS, Ctr Europeen Rech Imagerie Med CERIMED, Marseille, France

[7] Aix Marseille Univ, Inst Paoli Calmettes, INSERM, CNRS,CRCM, Marseille, France

[8] Univ Lodz, Fac Biol & Environm Protect, Dept Gen Biophys, Lodz, Poland

来源：

CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 02期

基金：

欧盟地平线“2020”;

关键词：

D O I：

10.1039/c9cc07750b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Bioimaging has revolutionized modern medicine, and nanotechnology can offer further specific and sensitive imaging. We report here an amphiphilic dendrimer able to self-assemble into supramolecular nanomicelles for effective tumor detection using SPECT radioimaging. This highlights the promising potential of supramolecular dendrimer platforms for biomedical imaging.

引用

页码：301 / 304

页数：4

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