A self-assembling amphiphilic dendrimer nanotracer for SPECT imaging

被引:21
|
作者
Ding, Ling [1 ,2 ]
Lyu, Zhenbin [1 ]
Tintaru, Aura [3 ]
Laurini, Erik [4 ]
Marson, Domenico [4 ]
Louis, Beatrice [5 ,6 ]
Bouhlel, Ahlem [5 ,6 ]
Balasse, Laure [5 ,6 ]
Fernandez, Samantha [5 ,6 ]
Garrigue, Philippe [5 ,6 ]
Mas, Eric [7 ]
Giorgio, Suzanne [1 ]
Pricl, Sabrina [2 ,8 ]
Guillet, Benjamin [5 ,6 ]
Peng, Ling [1 ]
机构
[1] Aix Marseille Univ, CNRS, Ctr Interdisciplinaire Nanosci Marseille, UMR 7325,Equipe Labellisee Ligue Canc, Marseille, France
[2] Aix Marseille Univ, CRMBM, CNRS, Marseille, France
[3] Aix Marseille Univ, Inst Chim Radicalaire, CNRS, UMR7273, Marseille, France
[4] Univ Trieste, DEA, Mol Biol & Nanotechnol Lab MolBNL UniTS, Trieste, Italy
[5] Aix Marseille Univ, C2VN, INRA, INSERM, Marseille, France
[6] Aix Marseille Univ, CNRS, Ctr Europeen Rech Imagerie Med CERIMED, Marseille, France
[7] Aix Marseille Univ, Inst Paoli Calmettes, INSERM, CNRS,CRCM, Marseille, France
[8] Univ Lodz, Fac Biol & Environm Protect, Dept Gen Biophys, Lodz, Poland
基金
欧盟地平线“2020”;
关键词
D O I
10.1039/c9cc07750b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Bioimaging has revolutionized modern medicine, and nanotechnology can offer further specific and sensitive imaging. We report here an amphiphilic dendrimer able to self-assemble into supramolecular nanomicelles for effective tumor detection using SPECT radioimaging. This highlights the promising potential of supramolecular dendrimer platforms for biomedical imaging.
引用
收藏
页码:301 / 304
页数:4
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