Integrative Multi-Omics Through Bioinformatics

被引:12
|
作者
Goh, Hoe-Han [1 ]
机构
[1] Univ Kebangsaan Malaysia, Inst Syst Biol, Bangi, Selangor, Malaysia
来源
关键词
Genome-scale model; Omics integration; Multi-omics; Network analysis; Systems metabolic engineering; METABOLIC NETWORK RECONSTRUCTION; FLUX VARIABILITY ANALYSIS; RNA-SEQ ANALYSIS; METHYL JASMONATE; POLYGONUM-MINUS; STORAGE SYNTHESIS; ESCHERICHIA-COLI; PLANT; MODEL; ACID;
D O I
10.1007/978-3-319-98758-3_5
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
This chapter introduces different aspects of bioinformatics with a brief discussion in the systems biology context. Example applications in network pharmacology of traditional Chinese medicine, systems metabolic engineering, and plant genome-scale modelling are described. Lastly, this chapter concludes on how bioinformatics helps to integrate omics data derived from various studies described in previous chapters for a holistic understanding of secondary metabolite production in P. minus.
引用
收藏
页码:69 / 80
页数:12
相关论文
共 50 条
  • [41] Integrative multi-omics characterization reveals sex differences in glioblastoma
    Byunghyun Jang
    Dayoung Yoon
    Ji Yoon Lee
    Jiwon Kim
    Jisoo Hong
    Harim Koo
    Jason K. Sa
    Biology of Sex Differences, 15
  • [42] MODMatcher: Multi-Omics Data Matcher for Integrative Genomic Analysis
    Yoo, Seungyeul
    Huang, Tao
    Campbell, Joshua D.
    Lee, Eunjee
    Tu, Zhidong
    Geraci, Mark W.
    Powell, Charles A.
    Schadt, Eric E.
    Spira, Avrum
    Zhu, Jun
    PLOS COMPUTATIONAL BIOLOGY, 2014, 10 (08)
  • [43] Integrative Multi-Omics Approach for Improving Causal Gene Identification
    King, Austin
    Wu, Chong
    GENETIC EPIDEMIOLOGY, 2025, 49 (01)
  • [44] Integrative multi-omics database (iMOMdb) of Asian pregnant women
    Pan, Hong
    Tan, Pei Fang
    Lim, Ives Y.
    Huan, Jason
    Teh, Ai Ling
    Chen, Li
    Gong, Min
    Tin, Felicia
    Mir, Sartaj Ahmad
    Narasimhan, Kothandaraman
    Chan, Jerry K. Y.
    Tan, Kok Hian
    Kobor, Michael S.
    Meikle, Peter J.
    Wenk, Markus R.
    Chong, Yap Seng
    Eriksson, Johan G.
    Gluckman, Peter D.
    Karnani, Neerja
    HUMAN MOLECULAR GENETICS, 2022,
  • [45] Editorial: Integrative genetics and multi-omics of complex human disorders
    Gui, Hongsheng
    Lessard, Christopher J.
    Liu, Jinhui
    Li, Miaoxin
    Adrianto, Indra
    FRONTIERS IN GENETICS, 2025, 16
  • [46] Integrative multi-omics database (iMOMdb) of Asian pregnant women
    Pan, Hong
    Tan, Pei Fang
    Lim, Ives Y.
    Huan, Jason
    Teh, Ai Ling
    Chen, Li
    Gong, Min
    Tin, Felicia
    Mir, Sartaj Ahmad
    Narasimhan, Kothandaraman
    Chan, Jerry K. Y.
    Tan, Kok Hian
    Kobor, Michael S.
    Meikle, Peter J.
    Wenk, Markus R.
    Chong, Yap Seng
    Eriksson, Johan G.
    Gluckman, Peter D.
    Karnani, Neerja
    HUMAN MOLECULAR GENETICS, 2022, 31 (18) : 3051 - 3067
  • [47] Integrative Multi-omics Analysis to Characterize Human Brain Ischemia
    Laura Ramiro
    Teresa García-Berrocoso
    Ferran Briansó
    Leire Goicoechea
    Alba Simats
    Víctor Llombart
    Ricardo Gonzalo
    Alexandre Hainard
    Elena Martínez-Saez
    Francesc Canals
    Jean-Charles Sanchez
    Alex Sánchez-Pla
    Joan Montaner
    Molecular Neurobiology, 2021, 58 : 4107 - 4121
  • [48] INTEGRATIVE MULTI-OMICS PROFILING IN PENILE SQUAMOUS CELL CARCINOMA
    Shaw, Timothy
    Obermayer, Alyssa
    Ercan, Dalia
    Stewart, Paul
    Chahoud, Jad
    Johnstone, Peter
    Spiess, Philippe
    Eschrich, Steven
    Grass, Daniel
    JOURNAL OF UROLOGY, 2023, 209 : E689 - E689
  • [49] Editorial: Integrative Approaches to Analyze Cancer Based on Multi-Omics
    Shen, Sipeng
    FRONTIERS IN GENETICS, 2022, 13
  • [50] Integrative multi-omics characterization of hepatocellular carcinoma in Hispanic patients
    Das, Debodipta
    Wang, Xiaojing
    Chiu, Yu-Chiao
    Bouamar, Hakim
    Sharkey, Francis E.
    Lopera, Jorge E.
    Lai, Zhao
    Weintraub, Susan T.
    Han, Xianlin
    Zou, Yi
    Chen, Hung-I H.
    Torrez, Carla R. Zeballos
    Gu, Xiang
    Cserhati, Matyas
    Michalek, Joel E.
    Halff, Glenn A.
    Chen, Yidong
    Zheng, Siyuan
    Cigarroa, Francisco G.
    Sun, Lu-Zhe
    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2024,