Atrial Fibrillation in Chronic Kidney Disease: An Overview

被引:11
作者
Gadde, Sai [1 ]
Kalluru, Revanth [1 ]
Cherukuri, Swathi Priya [2 ]
Chikatimalla, Rahul [1 ]
Dasaradhan, Thejaswi [2 ]
Koneti, Jancy [1 ]
机构
[1] Kamineni Inst Med Sci, Res, Narketpally, India
[2] Narayana Med Coll, Res, Nellore, India
关键词
thromboembolic stroke; inflammatory bio markers; cardiac remodelling; anti-arrhythmic medications; anti-coagulant therapy; chronic kidney disease (ckd); atrial fibrillation (af); NLRP3 INFLAMMASOME ACTIVATION; NATRIURETIC-PEPTIDE; CLINICAL-FEATURES; ACUTE MANAGEMENT; RENAL-FUNCTION; RISK-FACTORS; STROKE; MECHANISMS; WARFARIN; DYSFUNCTION;
D O I
10.7759/cureus.27753
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chronic kidney disease (CKD) is a condition that can be caused due to any etiology leading to structural damage to the kidney, which can be measured by a decrease in estimated glomerular filtration rate (eGFR) and the presence of damage biomarkers for more than three months. This article has discussed the causal relationship between atrial fibrillation (AF) and CKD, a few of them being inflammation, renin-angiotensinaldosterone system (RAAS) activation, anemia, and uremia associated with CKD. This review mentioned the clinical impact of the presence of AF in CKD patients. The presence of AF in CKD patients aggravates the renal dysfunction, which in turn adds to the generation of AF. This article explores the various pharmacological and interventional treatment modalities, including antiarrhythmics, anticoagulants, and cardiac ablation, and their complications, leading to restricted usage in CKD patients.
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页数:11
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