Photoacoustic endomicroscopy based on a MEMS scanning mirror

被引：53
作者：
Guo, Heng [1 ]
Song, Chaolong [3 ]
Xie, Huikai [4 ]
Xi, Lei [1 ,2 ]
机构：
[1] Univ Elect Sci & Technol China, Sch Phys Elect, Chengdu, Sichuan, Peoples R China
[2] Univ Elect Sci & Technol China, Ctr Informat Biomed, Chengdu, Sichuan, Peoples R China
[3] China Univ Geosci Wuhan, Sch Mech Engn & Elect Informat, Wuhan, Hubei, Peoples R China
[4] Univ Florida, Dept Elect & Comp Engn, Gainesville, FL 32611 USA
来源：
OPTICS LETTERS | 2017年 / 42卷 / 22期
基金：
中国国家自然科学基金;
关键词：
OPTICAL COHERENCE TOMOGRAPHY; IN-VIVO; MICROSCOPY; ORGANS;
D O I：
10.1364/OL.42.004615
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
In this Letter, we present a high-resolution photoacoustic endomicroscopy probe based on a microelectromechanical systems (MEMS) scanning mirror. The built-in optical assembly consists of a 0.7 mm graded-index (GRIN) lens for light focusing and a phi 1 mm MEMS mirror to reflect and scan the beam. A miniaturized unfocused ultrasound transducer with a center frequency of 10 MHz is used for photoacoustic detection. Sharp blades, carbon fibers, and black tapes were utilized to evaluate the performance of the system. In vivo mouse ears and resected rectums were imaged to further demonstrate the feasibility of this probe for potential biological and clinical applications. (C) 2017 Optical Society of America
引用
收藏
页码：4615 / 4618
页数：4
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