Evaluation of bone scaffolds by micro-CT

被引：46

作者：

Peyrin, F. ^{[1
,2
,3
]}

机构：

[1] ESRF, F-38043 Grenoble, France

[2] Univ Lyon 1, F-69622 Villeurbanne, France

[3] Inst Natl Sci Appl, INSERM, CREATIS, CNRS,UMR 5220,U1044, F-69621 Villeurbanne, France

来源：

OSTEOPOROSIS INTERNATIONAL | 2011年 / 22卷 / 06期

关键词：

Bone scaffolds; Microvascularization; Phase contrast; Synchrotron radiation micro-CT; Three dimensional imaging; X-ray micro-CT; X-RAY MICROTOMOGRAPHY; PHASE TOMOGRAPHY; TISSUE; NEOVASCULARIZATION; HOLOTOMOGRAPHY; MORPHOLOGY; RETRIEVAL; INGROWTH;

D O I：

10.1007/s00198-011-1609-y

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This paper reviews the possibilities offered by X-ray micro-CT in bone tissue engineering. This technique provides a fast, nondestructive, and 3D quantification of bone scaffolds, bone ingrowth, and microvascularization. Synchrotron radiation absorption and phase micro-CT offer additional advantages to image newly formed bone in bioceramic scaffolds and pre-bone matrix.

引用

页码：2043 / 2048

页数：6

共 27 条

[1]

Bernhardt R, 2004, Eur Cell Mater, V7, P42

[2] Development of in vivo μCT evaluation of neovascularisation in tissue engineered bone constructs [J].

Bolland, B. J. R. F. ;

Kanczler, J. M. ;

Dunlop, D. G. ;

Oreffo, R. O. C. .

BONE, 2008, 43 (01) :195-202

[3] Bulk and interface investigations of scaffolds and tissue-engineered bones by X-ray microtomography and X-ray microdiffraction [J].

Cancedda, R. ;

Cedola, A. ;

Giuliani, A. ;

Komlev, V. ;

Lagomarsino, S. ;

Mastrogiacomo, M. ;

Peyrin, F. ;

Rustichelli, F. .

BIOMATERIALS, 2007, 28 (15) :2505-2524

[4] Quantitative microcomputed tomography analysis of mineralization within three-dimensional scaffolds in vitro [J].

Cartmell, S ;

Huynh, K ;

Lin, A ;

Nagaraja, S ;

Guldberg, R .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2004, 69A (01) :97-104

[5] Holotomography: Quantitative phase tomography with micrometer resolution using hard synchrotron radiation x rays [J].

Cloetens, P ;

Ludwig, W ;

Baruchel, J ;

Van Dyck, D ;

Van Landuyt, J ;

Guigay, JP ;

Schlenker, M .

APPLIED PHYSICS LETTERS, 1999, 75 (19) :2912-2914

[6] Observation of microstructure and damage in materials by phase sensitive radiography and tomography [J].

Cloetens, P ;

PateyronSalome, M ;

Buffiere, JY ;

Peix, G ;

Baruchel, J ;

Peyrin, F ;

Schlenker, M .

JOURNAL OF APPLIED PHYSICS, 1997, 81 (09) :5878-5886

[7] Analyzing bone, blood vessels, and biomaterials with microcomputed tomography [J].

Guldberg, RE ;

Ballock, RT ;

Boyan, BD ;

Duvall, CL ;

Lin, ASP ;

Nagaraja, S ;

Oest, M ;

Phillips, J ;

Porter, BD ;

Robertson, G ;

Taylor, WR .

IEEE ENGINEERING IN MEDICINE AND BIOLOGY MAGAZINE, 2003, 22 (05) :77-83

[8] 3D imaging of tissue integration with porous biomaterials [J].

Guldberg, Robert E. ;

Duvall, Craig L. ;

Peister, Alexandra ;

Oest, Megan E. ;

Lin, Angela S. P. ;

Palmer, Ashley W. ;

Levenston, Marc E. .

BIOMATERIALS, 2008, 29 (28) :3757-3761

[9] A comparison of micro CT with other techniques used in the characterization of scaffolds [J].

Ho, ST ;

Hutmacher, DW .

BIOMATERIALS, 2006, 27 (08) :1362-1376

[10] Imaging and Quantitative Assessment of Long Bone Vascularization in the Adult Rat using Microcomputed Tomography [J].

Jia, Fei ;

Francoise, Peyrin ;

Malaval, Luc ;

Laurence, Vico ;

Lafage-Proust, Marie-Helene .

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, 2010, 293 (02) :215-224

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